Antiproteus antibody in rheumatoid arthritis versus systemic lupus erythematosus and osteaoarthitis

الملخص EN

This study was carried out to detect Proteus mirabilis antibodies in the serum of Egyptian patients suffering from RA, SLE and OA in order to find out its association with the three diseases if any.

The sample included 16 RA patients, 10 SLE patients, 11 0A patients and 10 healthy individuals.

Our results showed that anti Proteus antibody correlated positively with disease activity in RA when measured by the Stock index.

Also, it confirmed the relative specificity of this antibody to RA, as it was higher in RA than SLE, OA and controls.

Yet, it was higher in SLE patients than OA patients or controls and this difference was of highly statistical significance.

Again, the level of APA in OA was higher than that of controls and the difference was of high statistical significance.

These results support the suggested hypothesis that antiproteus antibody has a role in the pathogeneses of these disease especially RA.