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Angiotensin-converting enzyme inhibitors in hypertension and congestive heart failure
العناوين الأخرى
مثبطات إنزيم محول الأنجيوتنسين في حالات ارتفاع ضغط الدم و الأزمات القلبية
المصدر
Journal of King Abdulaziz University : Medical Sciences
العدد
المجلد 1، العدد 1 (31 ديسمبر/كانون الأول 1991)، ص ص. 3-8، 6ص.
الناشر
جامعة الملك عبد العزيز مركز النشر العلمي
تاريخ النشر
1991-12-31
دولة النشر
السعودية
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
-The place of angiotensin-converting enzyme (ACE) inhibition as first choice approach in the treatment of hypertension is now firmly established.
Clearly, if a patient with a totally asymptomatic disease is to be expected to comply with a life-long drug treatment meant to prevent future uncertain complications, he should, at least, be provided with a treatment that will not affect his present quality of life, and will not produce effects that may themselves become risk factors.
Accordingly, the perfect antihypertensive agent should have the following characteristics: it should lower systemic vascular resistance, the common mechanism by which all types of hypertension are sustained; it should maintain or improve regional blood flows to vital organs, i.e., insure adequate perfusion of the cerebral, coronary and renal vasculature; it should preserve optimal cardiac performance, i.e., it should have no negative effects on cardiac contractility and conductivity; it should prevent the retention of salt and fluid, a common side-effect of many antihypertensive agents, that may be partly responsible for “escape” of good blood pressure control; it should avoid reflex sympathetic activation, which adversely affects the heart’s economy; it should not interfere with various metabolic processes, such as glucose, electrolyte and lipid metabolism, i.e.
effects that have been incriminated in the failure of some drugs to prevent coronary complications; it should not interact with common drugs used to treat coexisting diseases, such as hypoglycemics, antidepressants, antiasthmatics,...
etc.; and finally, it should not adversely affect the psychosocial performance of otherwise healthy individuals leading active and demanding lives.
Obviously, no perfect drug exists yet, but ACE inhibitors come closest to fulfilling most of these re- Address correspondence io: Haralambos, Gavras, M.D., Chief Hypertension and Atherosclerosis Section, Boston University School of Medicine, L217, 80 East Concord Street, Boston, Massachusetts 02118, U.S.A.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gavras, Haralambos. 1991. Angiotensin-converting enzyme inhibitors in hypertension and congestive heart failure. Journal of King Abdulaziz University : Medical Sciences،Vol. 1, no. 1, pp.3-8.
https://search.emarefa.net/detail/BIM-399901
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gavras, Haralambos. Angiotensin-converting enzyme inhibitors in hypertension and congestive heart failure. Journal of King Abdulaziz University : Medical Sciences Vol. 1, no. 1 (1991), pp.3-8.
https://search.emarefa.net/detail/BIM-399901
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gavras, Haralambos. Angiotensin-converting enzyme inhibitors in hypertension and congestive heart failure. Journal of King Abdulaziz University : Medical Sciences. 1991. Vol. 1, no. 1, pp.3-8.
https://search.emarefa.net/detail/BIM-399901
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 6-7
رقم السجل
BIM-399901
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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