Some polarographic behaviour of ambilhur drug in different media (vitro)‎

الملخص EN

The polarographic behaviour of ambilhur (niridazole) [1-(5-Nitro-2-thiazolyl)- 2-imidazolidinone(I)] have been studied.

The drug give a well sensitive defined single peak at about -0.45V in carbonate buffer solution at pH 7.4 and -0.46V in serumcarbonate buffer and at -0.34V in urine-carbonate buffer.

The lowest determined concentration in aqueous carbonate buffer 9.1×10-7 M , in serum-carbonate buffer media was 5.4×10-7 M and 3.2×10-7 M in urine-carbonate media with correlation coefficient 0.998, 0.996, 0.999.

the relationship between concentration and diffusion current Ip was linear for all solutions.