Gastric carcinoma at tanta cancer center : a comparative retrospective clinico-pathological study of the elderly versus the non-elderly
المؤلفون المشاركون
Sabir, Majdi M.
al-Jamal, Dina
Sherisher, Muhammad A.
Ramadan, Hanan
Zayn al-Din, Ahmad A.
al-Jamal, Masad M.
المصدر
Journal of the Egyptian National Cancer Institute
العدد
المجلد 26، العدد 3 (30 سبتمبر/أيلول 2014)، ص ص. 127-137، 11ص.
الناشر
جامعة القاهرة المعهد القومي للأورام
تاريخ النشر
2014-09-30
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الموضوعات
الملخص EN
Background and aims : To study the clinico-pathological features, treatments and outcomes of gastric carcinoma (GC) in the elderly (P65 years) and the non-elderly Egyptian patients.
Methods : This retrospective cohort study included 168 patients with histologically confirmed GC treated at Tanta Cancer Center between 2003 and 2007.
Results : Compared to the non-elderly, elderly patients had significantly higher proportion of tumors involving the cardia (p = 0.034) and of adenocarcinoma NOS histology (p = 0.032).
Treatments were largely comparable in the two groups.
Response to palliative chemotherapy was achieved in 44.4 % of the elderly and 25.5 % of the non-elderly patients (p = 0.417).
The median overall survival (OS), disease-free survival (DFS) and progression-free survival (PFS) were 6, 17 and 3 months, respectively.
The median OS was 4 months in the elderly compared to 9 months in the non-elderly (p = 0.005).
The median DFS was 4 months in the elderly compared to 20 months in the non-elderly (p = 0.004).
The median PFS was 2 months in the elderly compared to 3 months in the non-elderly (p = 0.685).
In multivariate analysis, poor performance status was an independent predictor of poor OS, DFS and PFS.
Non-curative or no surgery and lack of chemotherapy use were independent predictors of poor OS.
Age was an independent predictor of poor DFS.
Conclusions : Compared to the non-elderly, GC in the elderly has similar clinico-pathological characteristics and exhibits comparable outcomes with the same treatment options.
Treatments should be tailored to each patient.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zayn al-Din, Ahmad A.& Ramadan, Hanan& al-Jamal, Masad M.& Sabir, Majdi M.& al-Jamal, Dina& Sherisher, Muhammad A.. 2014. Gastric carcinoma at tanta cancer center : a comparative retrospective clinico-pathological study of the elderly versus the non-elderly. Journal of the Egyptian National Cancer Institute،Vol. 26, no. 3, pp.127-137.
https://search.emarefa.net/detail/BIM-411896
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zayn al-Din, Ahmad A.…[et al.]. Gastric carcinoma at tanta cancer center : a comparative retrospective clinico-pathological study of the elderly versus the non-elderly. Journal of the Egyptian National Cancer Institute Vol. 26, no. 3 (2014), pp.127-137.
https://search.emarefa.net/detail/BIM-411896
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zayn al-Din, Ahmad A.& Ramadan, Hanan& al-Jamal, Masad M.& Sabir, Majdi M.& al-Jamal, Dina& Sherisher, Muhammad A.. Gastric carcinoma at tanta cancer center : a comparative retrospective clinico-pathological study of the elderly versus the non-elderly. Journal of the Egyptian National Cancer Institute. 2014. Vol. 26, no. 3, pp.127-137.
https://search.emarefa.net/detail/BIM-411896
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 136-137
رقم السجل
BIM-411896
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر