Corticosteroid in the treatment of moderate to severe thrombocytopenia due to leptospirosis
المؤلفون المشاركون
Alian, Shahriar
Asghari, Hasan
Najafi, Nargis
Davoudi, Alireza
Yazdani, Jamshid
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 16، العدد 10 (31 أكتوبر/تشرين الأول 2014)، ص ص. 1-6، 6ص.
الناشر
تاريخ النشر
2014-10-31
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : Thrombocytopenia is associated with a bad prognosis in Leptospirosis.
Objectives : We investigated the effect of corticosteroids to improve thrombocytopenia due to leptospirosis.
Patients and Methods : In a clinical trial, all patients admitted with leptospirosis in Razi Hospital of Ghaemshahr, north of Iran were enrolled in a 2-year study.
Totally, 56 patients with moderate to severe thrombocytopenia were randomized to control and treatment groups.
The treatment group received corticosteroid (prednisolone 1 mg / kg / day for maximum one week) in addition to the standard antibiotic therapy.
Results : There was no significant difference regarding age and gender between the two groups (P = 0.254, P = 0.789, respectively).
The mean duration to improve thrombocytopenia was 4.41 ± 0.197 days in the treatment group and 5.72 ± 0.318 days in the control group, which was significantly different (P = 0.003).
Duration of hospitalization in the treatment group was 5.24 ± 0.244 days and 6.23 ± 0.329 days in the control group, which was significantly different (P = 0.028).
The two groups had no significant difference regarding mortality, intubation, level of platelet, duration of ICU admission and pulmonary, renal or hepatic involvement.
Conclusions : Corticosteroid therapy decreased the length of hospitalization only in severe subgroup thrombocytopenia, but not in the moderate subgroup.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Alian, Shahriar& Asghari, Hasan& Najafi, Nargis& Davoudi, Alireza& Yazdani, Jamshid. 2014. Corticosteroid in the treatment of moderate to severe thrombocytopenia due to leptospirosis. Iranian Red Crescent Medical Journal،Vol. 16, no. 10, pp.1-6.
https://search.emarefa.net/detail/BIM-416817
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Alian, Shahriar…[et al.]. Corticosteroid in the treatment of moderate to severe thrombocytopenia due to leptospirosis. Iranian Red Crescent Medical Journal Vol. 16, no. 10 (Oct. 2014), pp.1-6.
https://search.emarefa.net/detail/BIM-416817
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Alian, Shahriar& Asghari, Hasan& Najafi, Nargis& Davoudi, Alireza& Yazdani, Jamshid. Corticosteroid in the treatment of moderate to severe thrombocytopenia due to leptospirosis. Iranian Red Crescent Medical Journal. 2014. Vol. 16, no. 10, pp.1-6.
https://search.emarefa.net/detail/BIM-416817
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 5-6
رقم السجل
BIM-416817
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر