Effect of probiotic hummus on blood lipids of rats

الملخص EN

The present study investigates the synbiotic effect of probiotic bacteria and hummus as a prebiotic on blood lipids in Sprague-Dawley rats.

A developed probiotic hummus that contained Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bb-12 was added to a previously heated hummus at 75ºC / 5 min., followed by an anaerobic incubation at 37ºC / 8 h.

The experimental diets included cholesterol diet, probiotic + cholesterol diet, hummus + cholesterol diet and probiotic hummus + cholesterol diet.

Animals were divided randomly, according to their weights, into four groups (8 rats / group).

Each group of the rats was fed one of the four diets for 8 weeks.

Inclusion of probiotics to the cholesterol diet showed hypocholesterolemic effect, since it significantly (p < 0.05) decreased TC and LDL-C by 14.5 % (from 73.38 to 62.75) and 28.5% (from 19.70P Pto 14.08), respectively, as compared with the control group.

No significant effects (p > 0.05) in HDL-C and TG were shown due to this inclusion.

The hummus addition to the cholesterol diet caused a significant (p <0.05) reduction of 9.0 % (from 73.38 to 66.75), 22.1 % (from 19.70P Pto 15.35) and 14.0 % (from 93.88 to 80.75) in TC, LDL-C and TG, respectively.

The combined effects of probiotics and prebiotics in probiotic hummus + cholesterol diet caused significant (p < 0.05) reductions of 14.1 % (from 73.38 to 63.00), 27.5 % (from 19.70P Pto 14.29) and 24.4 % (from 93.88 to 71.00) in TC, LDL-C and TG, respectively.

It could be concluded that the addition of probiotic hummus to the cholesterol-rich diet caused significant reductions in TC, LDL-C and TG.

However, these reductions were not significantly different from those reductions caused by the addition of probiotic or hummus alone except for TG.