Epstien-barr viral infection in renal allograft recipients : a single center experience
المؤلفون المشاركون
Zadah, Zaki Rustum
Makhdumi, Khadijah
Lak, Shakir Sari
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 17، العدد 3 (30 يونيو/حزيران 2006)، ص ص. 351-354، 4ص.
الناشر
تاريخ النشر
2006-06-30
دولة النشر
السعودية
عدد الصفحات
4
التخصصات الرئيسية
الموضوعات
الملخص EN
In this study we attempted to identify the factors involved in Epstein-Barr viral (EBV) infection among renal allograft recipients.
We studied 68 renal allograft recipients hospitalized at the Imam Khomeini Medical Center from 2001 to 2004.
Blood samples were obtained from the patients before renal transplantation and repeated every 3 months during the first year after transplantation.
Enzyme linked immunosorbant assay (ELISA) tests were performed on these samples to determine if antibodies to EBV antigens, such as viral capsid antigen (VCA) IgM, VCAIgG or Epstein Barr neoantigen (EBNA)IgG, were present.
The types of prescribed immunosuppressive agents and the incidence of acute allograft rejection were closely observed to define their association with EBV.
EBV infection developed in 58 (85.3 %) patients and active disease in 10 (14.7 %).
EBV was detected in 40 (58.8 %) patients during the first year after transplantation.
There was EBNAIgG seropositivity in 65 (95.6 %) patients before transplantation ; this number increased to 68 (100 %) after transplantation.
In contrast, VCAIgG seropositivity increased from 92.6 % before transplantation to 96.9 % after transplantation ; whereas VCAIgM seropositivity increased from 17.6 % before transplantation to 58.8 % after transplantation.
There were no statistically significant differences in the reactivation of EBV infection between the different immunosuppressive regimens, between the groups of acute rejection and no acute rejection, or between the groups that received and did not receive anti-lymphocyte globulin (ALG) We conclude that most EBV activation after transplantation may represent a secondary form of a preexisting infection and we could not find a clear association with a specific immunosuppressive regimen, including the use of ALG.
Further investigation is thus required to elucidate the factors involved in the reactivation of the EBV infection in the transplant population.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zadah, Zaki Rustum& Makhdumi, Khadijah& Lak, Shakir Sari. 2006. Epstien-barr viral infection in renal allograft recipients : a single center experience. Saudi Journal of Kidney Diseases and Transplantation،Vol. 17, no. 3, pp.351-354.
https://search.emarefa.net/detail/BIM-43400
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zadah, Zaki Rustum…[et al.]. Epstien-barr viral infection in renal allograft recipients : a single center experience. Saudi Journal of Kidney Diseases and Transplantation Vol. 17, no. 3 (Dec. 2006), pp.351-354.
https://search.emarefa.net/detail/BIM-43400
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zadah, Zaki Rustum& Makhdumi, Khadijah& Lak, Shakir Sari. Epstien-barr viral infection in renal allograft recipients : a single center experience. Saudi Journal of Kidney Diseases and Transplantation. 2006. Vol. 17, no. 3, pp.351-354.
https://search.emarefa.net/detail/BIM-43400
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 354
رقم السجل
BIM-43400
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر