In Vivo Potential Anti-Inflammatory Activity of Melissa officinalis L. Essential Oil
المؤلفون المشاركون
Cherrah, Yahia
Alnamer, Rachad
Zellou, Amina
Bounihi, Amina
Hajjaj, Ghizlane
المصدر
Advances in Pharmacological Sciences
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-05
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Melissa officinalis L.
(Lamiaceae) had been reported in traditional Moroccan medicine to exhibit calming, antispasmodic, and strengthening heart effects.
Therefore, this study is aimed at determining the anti-inflammatory activities of M.
officinalis L.
leaves.
The effect of the essential oil of the leaves of this plant was investigated for anti-inflammatory properties by using carrageenan and experimental trauma-induced hind paw edema in rats.
The essential oil extracted from leaves by hydrodistillation was characterized by means of gas chromatography-mass spectrometry (GC-MS).
M.
officinalis contained Nerol (30.44%), Citral (27.03%), Isopulegol (22.02%), Caryophyllene (2.29%), Caryophyllene oxide (1.24%), and Citronella (1.06%).
Anti-inflammatory properties of oral administration of essential oil at the doses of 200, 400 mg/kg p.o., respectively, showed significant reduction and inhibition of edema with 61.76% and 70.58%, respectively, (P<0.001) induced by carrageenan at 6 h when compared with control and standard drug (Indomethacin).
On experimental trauma, M.
officinalis L.
essential oil showed pronounced reduction and inhibition of edema induced by carrageenan at 6 h at 200 and 400 mg/kg with 91.66% and 94.44%, respectively (P<0.001).
We can conclude that the essential oil of M.
officinalis L.
possesses potential anti-inflammatory activities, supporting the traditional application of this plant in treating various diseases associated with inflammation and pain.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bounihi, Amina& Hajjaj, Ghizlane& Alnamer, Rachad& Cherrah, Yahia& Zellou, Amina. 2013. In Vivo Potential Anti-Inflammatory Activity of Melissa officinalis L. Essential Oil. Advances in Pharmacological Sciences،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-446401
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bounihi, Amina…[et al.]. In Vivo Potential Anti-Inflammatory Activity of Melissa officinalis L. Essential Oil. Advances in Pharmacological Sciences No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-446401
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bounihi, Amina& Hajjaj, Ghizlane& Alnamer, Rachad& Cherrah, Yahia& Zellou, Amina. In Vivo Potential Anti-Inflammatory Activity of Melissa officinalis L. Essential Oil. Advances in Pharmacological Sciences. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-446401
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-446401
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر