Evaluation of a Bladder Cancer Cluster in a Population of Criminal Investigators with the Bureau of Alcohol, Tobacco, Firearms and Explosives—Part 1 : The Cancer Incidence

الملخص EN

This study investigated a bladder cancer cluster in a cohort of employees, predominately criminal investigators, participating in a medical surveillance program with the United States Bureau of Alcohol, Tobacco, Firearms and Explosives (ATF) between 1995 and 2007.

Standardized incidence ratios (SIRs) were used to compare cancer incidences in the ATF population and the US reference population.

Seven cases of bladder cancer (five cases verified by pathology report at time of analysis) were identified among a total employee population of 3,768 individuals.

All cases were white males and criminal investigators.

Six of seven cases were in the 30 to 49 age range at the time of diagnosis.

The SIRs for white male criminal investigators undergoing examinations were 7.63 (95% confidence interval = 3.70–15.75) for reported cases and 5.45 (2.33–12.76) for verified cases.

White male criminal investigators in the ATF population are at statistically significant increased risk for bladder cancer.