Morphostructural MRI Abnormalities Related to Neuropsychiatric Disorders Associated to Multiple Sclerosis
المؤلفون المشاركون
Gallo, Antonio
Tedeschi, Gioacchino
Bonavita, Simona
المصدر
Multiple Sclerosis International
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-04-16
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Multiple Sclerosis associated neuropsychiatric disorders include major depression (MD), obsessive-compulsive disorder (OCD), bipolar affective disorder, euphoria, pseudobulbar affect, psychosis, and personality change.
Magnetic Resonance Imaging (MRI) studies focused mainly on identifying morphostructural correlates of MD; only a few anecdotal cases on OCD associated to MS (OCD-MS), euphoria, pseudobulbar affect, psychosis, personality change, and one research article on MRI abnormalities in OCD-MS have been published.
Therefore, in the present review we will report mainly on neuroimaging abnormalities found in MS patients with MD and OCD.
All together, the studies on MD associated to MS suggest that, in this disease, depression is linked to a damage involving mainly frontotemporal regions either with discrete lesions (with those visible in T1 weighted images playing a more significant role) or subtle normal appearing white matter abnormalities.
Hippocampal atrophy, as well, seems to be involved in MS related depression.
It is conceivable that grey matter pathology (i.e., global and regional atrophy, cortical lesions), which occurs early in the course of disease, may involve several areas including the dorsolateral prefrontal cortex, the orbitofrontal cortex, and the anterior cingulate cortex whose disruption is currently thought to explain late-life depression.
Further MRI studies are necessary to better elucidate OCD pathogenesis in MS.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bonavita, Simona& Tedeschi, Gioacchino& Gallo, Antonio. 2013. Morphostructural MRI Abnormalities Related to Neuropsychiatric Disorders Associated to Multiple Sclerosis. Multiple Sclerosis International،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-446464
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bonavita, Simona…[et al.]. Morphostructural MRI Abnormalities Related to Neuropsychiatric Disorders Associated to Multiple Sclerosis. Multiple Sclerosis International No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-446464
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bonavita, Simona& Tedeschi, Gioacchino& Gallo, Antonio. Morphostructural MRI Abnormalities Related to Neuropsychiatric Disorders Associated to Multiple Sclerosis. Multiple Sclerosis International. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-446464
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-446464
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر