Role of Surrogate Markers of Atherosclerosis in Clinical and Subclinical Thyroidism
المؤلفون المشاركون
Ozkaya, Mesut
Kircelli, Fatih
Gunduz, Mehmet
Gunduz, Ercan
Okur, Nazan
المصدر
International Journal of Endocrinology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-02-23
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Data on the relationship between homocysteine, plasminogen activator inhibitor 1, hs-CRP, fibrinogen, and carotid intima media thickness (CA-IMT) is plenty but contradicting and the majority of the studies investigated this issue in only specific thyroidism groups.
The aim of this paper was to investigate these relations in patients with subclinical and clinical hypo- and hyperthyroidism.
Methods.
In this cross-sectional study, 16 patients from each thyroidism group and 20 healthy cases were enrolled.
Fibrinogen levels and plasminogen activator inhibitor 1 (PAI-1) activity were assessed.
CA-IMT was determined by gray-scale high-resolution color Doppler ultrasound.
Results.
Serum homocysteine levels were higher in hypothyroidic patients compared to the control (P=0.003).
Fibrinogen levels were higher in patients with subclinical hypothyroidism compared to other groups (P<0.05).
There was no difference between groups regarding PAI-1.
Whereas total cholesterol, homocysteine, and LDL were correlated with CAIMT, hs-CRP, PAI-1, and fibrinogen were not.
In the clinical hypothyroidism group, the correlation of homocysteine with CA-IMT was derived from the correlation between CA-IMT and homocysteine.
Conclusions.
Homocysteine and fibrinogen levels are higher in patients with clinical and subclinical hypothyroidism, respectively.
Homocysteine level is associated with CA-IMTonly in patients with clinical hypothyroidism.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gunduz, Mehmet& Gunduz, Ercan& Kircelli, Fatih& Okur, Nazan& Ozkaya, Mesut. 2012. Role of Surrogate Markers of Atherosclerosis in Clinical and Subclinical Thyroidism. International Journal of Endocrinology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-447195
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gunduz, Mehmet…[et al.]. Role of Surrogate Markers of Atherosclerosis in Clinical and Subclinical Thyroidism. International Journal of Endocrinology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-447195
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gunduz, Mehmet& Gunduz, Ercan& Kircelli, Fatih& Okur, Nazan& Ozkaya, Mesut. Role of Surrogate Markers of Atherosclerosis in Clinical and Subclinical Thyroidism. International Journal of Endocrinology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-447195
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-447195
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر