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Resistance Training and Testosterone Levels in Male Patients with Chronic Kidney Disease Undergoing Dialysis
المؤلفون المشاركون
Eidemak, Inge
Andersen, Jesper L.
Harrison, Adrian P.
Molsted, Stig
Jørgensen, Niels
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-04-03
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
We investigated serum testosterone and insulin-like growth factor 1 (IGF-1) levels’ associations with muscle fibre size and resistance training in male dialysis patients.
Methods.
Male patients were included in a 16-week control period followed by 16 weeks of resistance training thrice weekly.
Blood samples were obtained to analyse testosterone, luteinizing hormone (LH), IGF-1, and IGF-binding protein 3.
Muscle fibres’ size was analysed in biopsies from m.
vastus lateralis.
Results.
The patients’ testosterone levels were within the normal range at baseline (n=20) (19.5 (8.2–52.1) nmol/L versus 17.6 (16.1–18.0), resp.) whereas LH levels were higher (13.0 (5.5–82.8) U/L versus 4.3 (3.3–4.6), P<0.001, resp.).
IGF-1 and IGF-binding protein 3 levels were higher in the patients compared with reference values (203 (59–590) ng/mL versus 151 (128–276), P=0.014, and 5045 (3370–9370) ng/mL versus 3244 (3020–3983), P<0.001, resp.).
All hormone levels and muscle fibre size (n=12) remained stable throughout the study.
Age-adjusted IGF-1 was associated with type 1 and 2 fibre sizes (P<0.05).
Conclusion.
Patients’ total testosterone values were normal due to markedly increased LH values, which suggest a compensated primary insufficiency of the testosterone producing Leydig cell.
Even though testosterone values were normal, resistance training was not associated with muscle hypertrophy.
This trial is registered with ISRCTN72099857.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Molsted, Stig& Andersen, Jesper L.& Eidemak, Inge& Harrison, Adrian P.& Jørgensen, Niels. 2014. Resistance Training and Testosterone Levels in Male Patients with Chronic Kidney Disease Undergoing Dialysis. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-447308
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Molsted, Stig…[et al.]. Resistance Training and Testosterone Levels in Male Patients with Chronic Kidney Disease Undergoing Dialysis. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-447308
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Molsted, Stig& Andersen, Jesper L.& Eidemak, Inge& Harrison, Adrian P.& Jørgensen, Niels. Resistance Training and Testosterone Levels in Male Patients with Chronic Kidney Disease Undergoing Dialysis. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-447308
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-447308
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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