Survival Implications Associated with Variation in Mastectomy Rates for Early-Staged Breast Cancer
المؤلفون المشاركون
Winer, Eric P.
Fang, Gang
Landrum, Mary Beth
Chrischilles, Elizabeth A.
Keating, Nancy L.
Brooks, John M.
Wright, Kara B.
المصدر
International Journal of Surgical Oncology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-08-08
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Despite a 20-year-old guideline from the National Institutes of Health (NIH) Consensus Development Conference recommending breast conserving surgery with radiation (BCSR) over mastectomy for woman with early-stage breast cancer (ESBC) because it preserves the breast, recent evidence shows mastectomy rates increasing and higher-staged ESBC patients are more likely to receive mastectomy.
These observations suggest that some patients and their providers believe that mastectomy has advantages over BCSR and these advantages increase with stage.
These beliefs may persist because the randomized controlled trials (RCTs) that served as the basis for the NIH guideline were populated mainly with lower-staged patients.
Our objective is to assess the survival implications associated with mastectomy choice by patient alignment with the RCT populations.
We used instrumental variable methods to estimate the relationship between surgery choice and survival for ESBC patients based on variation in local area surgery styles.
We find results consistent with the RCTs for patients closely aligned to the RCT populations.
However, for patients unlike those in the RCTs, our results suggest that higher mastectomy rates are associated with reduced survival.
We are careful to interpret our estimates in terms of limitations of our estimation approach.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Brooks, John M.& Chrischilles, Elizabeth A.& Landrum, Mary Beth& Wright, Kara B.& Fang, Gang& Winer, Eric P.…[et al.]. 2012. Survival Implications Associated with Variation in Mastectomy Rates for Early-Staged Breast Cancer. International Journal of Surgical Oncology،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-447842
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Brooks, John M.…[et al.]. Survival Implications Associated with Variation in Mastectomy Rates for Early-Staged Breast Cancer. International Journal of Surgical Oncology No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-447842
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Brooks, John M.& Chrischilles, Elizabeth A.& Landrum, Mary Beth& Wright, Kara B.& Fang, Gang& Winer, Eric P.…[et al.]. Survival Implications Associated with Variation in Mastectomy Rates for Early-Staged Breast Cancer. International Journal of Surgical Oncology. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-447842
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-447842
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر