Adaption and Application of the Four Phase Trials to Traditional Chinese Medicines
المؤلفون المشاركون
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-08-20
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Four phases of trial are widely used in testing drugs, surgery, and diagnosis in Western medicine (WM).
The staged testing process helps protect patients from unnecessary harms and control costs while assessing safety and efficacy.
In this paper we adapt the four phase trials for traditional Chinese medicine (TCM).
As TCM has been used in humans for thousands of years and there has been good preliminary clinical evidence on safety and efficacy for many of its therapies, in most cases its evaluation can start directly in humans, and preclinical laboratory research can be conducted in phase 4 trials after the efficacy is firmly demonstrated.
Furthermore, unlike investigational drugs, TCM therapies are various in the certainty of their safety and efficacy and thus should not enter the evaluation process at the same stage.
Unlike in WM, clarifying and refining PICO (patients, intervention, comparator, and outcome) are an important part of evaluation of newly designed TCM therapies.
The incommensurability between WM and TCM causes additional difficulties in TCM trials regarding defining and choosing PICO, for which some suggestions are made.
Observational studies seem to have a greater role in evaluation for TCM although the efficacy must be confirmed with randomized trials.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Di, M. Y.& Tang, Jin Ling. 2013. Adaption and Application of the Four Phase Trials to Traditional Chinese Medicines. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-447853
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Di, M. Y.& Tang, Jin Ling. Adaption and Application of the Four Phase Trials to Traditional Chinese Medicines. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-447853
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Di, M. Y.& Tang, Jin Ling. Adaption and Application of the Four Phase Trials to Traditional Chinese Medicines. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-447853
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-447853
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر