Cellular Mediators of Inflammation : Tregs and TH17 Cells in Gastrointestinal Diseases
المؤلفون المشاركون
Cianci, Rossella
Pagliari, Danilo
Landolfi, Raffaele
Cammarota, Giovanni
Pandolfi, Franco
المصدر
العدد
المجلد 2009، العدد 2009 (31 ديسمبر/كانون الأول 2009)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-02-08
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Human lymphocyte subpopulations were originally classified as T- and B-cells in the 70s.
Later, with the development of monoclonal antibodies, it became possible to recognize, within the T-cells, functional populations: CD4+ and CD8+.
These populations were usually referred to as “helper” and “suppressor” cells, respectively.
However several investigations within the CD8 cells failed to detect a true suppressor activity.
Therefore the term suppressor was neglected because it generated confusion.
Much later, true suppressor activity was recognized in a subpopulation of CD4 cells characterized by high levels of CD25.
The novel population is usually referred to as T regulatory cells (Tregs) and it is characterized by the expression of FoxP3.
The heterogeneity of CD4 cells was further expanded by the recent description of a novel subpopulation characterized by production of IL-17.
These cells are generally referred to as TH17.
They contribute to regulate the overall immune response together with other cytokine-producing populations.
Treg and TH17 cells are related because they could derive from a common progenitor, depending on the presence of certain cytokines.
The purpose of this review is to summarize recent findings of the role of these novel populations in the field of human gastroenterological disease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pandolfi, Franco& Cianci, Rossella& Pagliari, Danilo& Landolfi, Raffaele& Cammarota, Giovanni. 2010. Cellular Mediators of Inflammation : Tregs and TH17 Cells in Gastrointestinal Diseases. Mediators of Inflammation،Vol. 2009, no. 2009, pp.1-11.
https://search.emarefa.net/detail/BIM-448216
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pandolfi, Franco…[et al.]. Cellular Mediators of Inflammation : Tregs and TH17 Cells in Gastrointestinal Diseases. Mediators of Inflammation No. 2009 (2009), pp.1-11.
https://search.emarefa.net/detail/BIM-448216
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pandolfi, Franco& Cianci, Rossella& Pagliari, Danilo& Landolfi, Raffaele& Cammarota, Giovanni. Cellular Mediators of Inflammation : Tregs and TH17 Cells in Gastrointestinal Diseases. Mediators of Inflammation. 2010. Vol. 2009, no. 2009, pp.1-11.
https://search.emarefa.net/detail/BIM-448216
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-448216
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر