Cardiovascular Protective Effects of Adjunctive Alternative Medicine (Salvia miltiorrhiza and Pueraria lobata) in High-Risk Hypertension
المؤلفون المشاركون
Chan, Thomas Y. K.
Yip, Thomas W. C.
Chook, Ping
Leung, Ping-Chung
Szeto, C. C.
Woo, Kam-Sang
Kwong, S. K.
Cheng, William King-Fai
Li, June K. Y.
Fung, Kwok Pui
Yu, Alex W. Y.
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-03-07
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Introduction.
Hypertension in association with diabetes (DM), renal impairment (RI), and left ventricular hypertrophy (LVH) increases the risk of future cardiovascular events.
We hypothesize, traditional herbal medicines Danshen and Gegen (D&G) have beneficial effects on atherogenesis in these high-risk hypertensive subjects.
Subjects and Methods.
90 asymptomatic hypertensive subjects associated with LVH (63.3%), DM (62.2%), or RI (30%) were randomized to receive D&G herbal capsules 1 gm/day, 2 gm/day, or identical placebo capsules in double-blind and parallel fashion for 12 months.
Brachial flow-mediated dilation (endothelium-dependent dilation, FMD) and carotid intima-media thickness (IMT) were measured by ultrasound.
All data were analyzed using the Statistical Package for Social Sciences in Windows 16.0.
Results.
Their mean age was 55±8 years, and 74.4% were male.
After 12 months of adjunctive therapies and compared with baseline, there were no significant changes in blood pressure, heart rate, hematological, glucose, and creatinine profiles in both placebo and D&G groups.
FMD improved significantly during D&G (P=0.0001) and less so after placebo treatment (P=0.001).
There was a mild but significant decrease in carotid IMT after D&G (P<0.001) but no significant changes after placebo.
A trend of better improvement in FMD after higher versus lower D&G dosages was seen.
D&G were well tolerated, with no significant adverse events or blood biochemistry changes.
Conclusion.
D&G adjunctive treatment was well tolerated and significantly improved atherogenesis in high-risk hypertensive patients, with potential in primary atherosclerosis prevention.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Woo, Kam-Sang& Yip, Thomas W. C.& Chook, Ping& Kwong, S. K.& Szeto, C. C.& Li, June K. Y.…[et al.]. 2013. Cardiovascular Protective Effects of Adjunctive Alternative Medicine (Salvia miltiorrhiza and Pueraria lobata) in High-Risk Hypertension. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-448309
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Woo, Kam-Sang…[et al.]. Cardiovascular Protective Effects of Adjunctive Alternative Medicine (Salvia miltiorrhiza and Pueraria lobata) in High-Risk Hypertension. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-448309
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Woo, Kam-Sang& Yip, Thomas W. C.& Chook, Ping& Kwong, S. K.& Szeto, C. C.& Li, June K. Y.…[et al.]. Cardiovascular Protective Effects of Adjunctive Alternative Medicine (Salvia miltiorrhiza and Pueraria lobata) in High-Risk Hypertension. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-448309
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-448309
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر