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Cytotoxic Activity of Crude Extracts as well as of Pure Components from Jatropha Species, Plants Used Extensively in African Traditional Medicine
المؤلفون المشاركون
Schröder, Heinz C.
Taglialatela-Scafati, Orazio
Müller, Werner E. G.
Aiyelaagbe, Olapeju O.
Hamid, Amao A.
Fattorusso, Ernesto
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-06-15
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Extracts from Jatropha curcas, a plant used in African traditional medicine for various diseases, were tested for cytotoxic activity.
The root extracts strongly reduced cell growth of tumor cells in vitro, a result consistent with the knowledge of the application of these plant extracts in traditional medicine, especially to cure/ameliorate cancer.
A selection of pure diterpenoids existing in extracts from Jatropha species and isolated from J.
curcas, for example, curcusone C, curcusone D, multidione, 15-epi-4Z-jatrogrossidentadion, 4Z-jatrogrossidentadion, 4E-jatrogrossidentadion, 2-hydroxyisojatrogrossidion, and 2-epi-hydroxyisojatrogrossidion, were likewise tested, and they also showed strong cytotoxic activity.
It turned out that these extracts are highly active against L5178y mouse lymphoma cells and HeLa human cervix carcinoma cells, while they cause none or only very low activity against neuronal cell, for example, PC12.
These data underscore that extracts from J.
curcas or pure secondary metabolites from the plant are promising candidates to be anticancer drug, combined with low neuroactive effects.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Aiyelaagbe, Olapeju O.& Hamid, Amao A.& Fattorusso, Ernesto& Taglialatela-Scafati, Orazio& Schröder, Heinz C.& Müller, Werner E. G.. 2011. Cytotoxic Activity of Crude Extracts as well as of Pure Components from Jatropha Species, Plants Used Extensively in African Traditional Medicine. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-448424
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Aiyelaagbe, Olapeju O.…[et al.]. Cytotoxic Activity of Crude Extracts as well as of Pure Components from Jatropha Species, Plants Used Extensively in African Traditional Medicine. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-448424
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Aiyelaagbe, Olapeju O.& Hamid, Amao A.& Fattorusso, Ernesto& Taglialatela-Scafati, Orazio& Schröder, Heinz C.& Müller, Werner E. G.. Cytotoxic Activity of Crude Extracts as well as of Pure Components from Jatropha Species, Plants Used Extensively in African Traditional Medicine. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-448424
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-448424
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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