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A Systematic Review and Meta-Analysis of Buyang Huanwu Decoction in Animal Model of Focal Cerebral Ischemia
المؤلفون المشاركون
Yin, Bo
Chu, Ke-tan
Wei, Rui-li
Xu, Yang
Teng, Hai-juan
He, Fang-pin
Du, Yue
Zheng, Guo-qing
Luo, Ben-yan
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-06-04
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Buyang Huanwu Decoction (BHD) is a well-known Chinese herbal prescription for ischemic stroke.
The objective of this systematic review and meta-analysis is to provide the current evidence for neuroprotective effects of BHD and its possible mechanisms in animal models of focal ischemia.
A systematic literature search, through October 2012, was performed using six databases.
The outcome measures assessed were infarct size and/or neurological score.
Fifty-six studies with 1270 animals that met the inclusion criteria were identified.
The median score for methodological quality was 3 with a range of 2 to 6.
Compared with vehicle or no treatment controls, BHD gave a 37% improvement in outcome for all doses ranging from 1.0 g/kg to 60 g/kg at each time point that BHD was administered (P<0.01).
Efficacy was higher in mouse models that utilized suture occlusion and temporary ischemia.
The neuroprotective effects of BHD are involved in multiple mechanisms and act upon multiple cell types.
In conclusion, BHD possesses substantial neuroprotective effects in experimental stroke probably as a result of the multitarget therapy strategy typically utilized in traditional Chinese medicine.
Future research should examine the presence of possible experimental bias and an in-depth study of herbal compound preparations.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wei, Rui-li& Teng, Hai-juan& Yin, Bo& Xu, Yang& Du, Yue& He, Fang-pin…[et al.]. 2013. A Systematic Review and Meta-Analysis of Buyang Huanwu Decoction in Animal Model of Focal Cerebral Ischemia. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-448767
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wei, Rui-li…[et al.]. A Systematic Review and Meta-Analysis of Buyang Huanwu Decoction in Animal Model of Focal Cerebral Ischemia. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-13.
https://search.emarefa.net/detail/BIM-448767
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wei, Rui-li& Teng, Hai-juan& Yin, Bo& Xu, Yang& Du, Yue& He, Fang-pin…[et al.]. A Systematic Review and Meta-Analysis of Buyang Huanwu Decoction in Animal Model of Focal Cerebral Ischemia. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-448767
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-448767
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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