Comparative Effects of Three Iron Chelation Therapies on the Quality of Life of Greek Patients with Homozygous Transfusion-Dependent Beta-Thalassemia
المؤلفون المشاركون
Kourakli-Symeonidis, Alexandra
Goulas, Vasilis
Camoutsis, Charalambos
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-12-17
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
This prospective study assessed the quality of life of patients with homozygous transfusion-dependent beta-thalassemia in Greece receiving three different iron chelation treatments.
Patients enrolled were receiving one of the following chelation therapies: deferoxamine (n=21), deferasirox (n=75), or deferoxamine in combination with deferiprone (n=39).
The three groups were compared in terms of their quality of life, satisfaction and adherence to treatment, control of their health, and self-esteem through the completion of five questionnaires.
A higher percentage of patients receiving deferoxamine felt that their treatment negatively influenced their body and skin appearance and limited their ability to work, attend school, and perform daily tasks (P=0.0066).
The adherence to treatment rate and self-esteem were the lowest in the deferoxamine group (P<0.05).
The deferoxamine group also had the lowest physical component summary score in the SF-36 questionnaire (P=0.014).
This study suggests that the quality of life of beta-thalassemia patients receiving chelation therapy is dependent on the type of iron chelation treatment they receive.
The study provides insight into important factors associated with the quality of life of these patients, which are essential for developing a more suitable clinical support team and counseling in order to maximize the treatment benefits for these patients in daily clinical practice.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Goulas, Vasilis& Kourakli-Symeonidis, Alexandra& Camoutsis, Charalambos. 2012. Comparative Effects of Three Iron Chelation Therapies on the Quality of Life of Greek Patients with Homozygous Transfusion-Dependent Beta-Thalassemia. ISRN Hematology،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-448901
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Goulas, Vasilis…[et al.]. Comparative Effects of Three Iron Chelation Therapies on the Quality of Life of Greek Patients with Homozygous Transfusion-Dependent Beta-Thalassemia. ISRN Hematology No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-448901
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Goulas, Vasilis& Kourakli-Symeonidis, Alexandra& Camoutsis, Charalambos. Comparative Effects of Three Iron Chelation Therapies on the Quality of Life of Greek Patients with Homozygous Transfusion-Dependent Beta-Thalassemia. ISRN Hematology. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-448901
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-448901
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر