Anti-Phospholipid Antibodies in Patients Undergoing Total Joint Replacement Surgery
المؤلفون المشاركون
Onitilo, Adedayo A.
Hocking, William
Burmester, James K.
Yale, Steven H.
Sanfelippo, Michael J.
Mazza, Joseph J.
Simpson, Melissa
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-10-31
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background.
Patients undergoing joint replacement remain at increased risk for venous thromboembolism (VTE) compared to other types of surgery, regardless of thromboprophylactic regimen.
The pathophysiologic processes rendering this group of patients at risk for VTE are multifactorial.
Procedure-specific and patient-specific exposures play a role in the postoperative development of VTE, including the development of anti-phospholipid antibodies (aPL).
Methods.
We measured three aPL (anti-cardiolipin, anti-β2 glycoprotein, and lupus anticoagulant) in 123 subjects undergoing total knee or hip arthroplasty to describe the presence of these antibodies preoperatively and to describe the rate of postoperative seroconversion among those people who were negative preoperatively.
Postoperative antibodies were measured at day 7, 14, and 21.
Results.
The prevalence of aPL antibodies in the preoperative period was 44%, positive subjects were more likely to be smokers (P=0.05) and were less likely to have undergone a previous arthroplasty procedure (P=0.002).
Subjects seroconverted in a 21 day postoperative period at a rate of 79%.
Conclusions.
These pilot data suggest that the prevalence of aPL in this population both preoperatively and postoperatively is higher than previously expected.
Further studies are needed to describe aPL in a larger population and to establish their clinical significance in populations undergoing joint replacement surgeries.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Simpson, Melissa& Sanfelippo, Michael J.& Onitilo, Adedayo A.& Burmester, James K.& Hocking, William& Yale, Steven H.…[et al.]. 2012. Anti-Phospholipid Antibodies in Patients Undergoing Total Joint Replacement Surgery. Thrombosis،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-449118
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Simpson, Melissa…[et al.]. Anti-Phospholipid Antibodies in Patients Undergoing Total Joint Replacement Surgery. Thrombosis No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-449118
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Simpson, Melissa& Sanfelippo, Michael J.& Onitilo, Adedayo A.& Burmester, James K.& Hocking, William& Yale, Steven H.…[et al.]. Anti-Phospholipid Antibodies in Patients Undergoing Total Joint Replacement Surgery. Thrombosis. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-449118
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-449118
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر