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Randomized Comparison of Isosorbide Mononitrate and PGE2 Gel for Cervical Ripening at Term including High Risk Pregnancy
المؤلفون المشاركون
Aggarwal, Abha
Batra, Aruna
Batra, Achla
Agarwal, Kavita
المصدر
International Journal of Reproductive Medicine
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-06-30
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Aims.
Prostaglandin E2 is the most commonly used drug for cervical ripening prior to labour induction.
However, there are concerns regarding uterine tachysystole and nonreassuring fetal heart (N-RFH).
Isosorbide mononitrate (IMN) has been used successfully for cervical ripening.
The present study was conducted to compare the two drugs for cervical ripening at term in hospital.
Methods.
Two hundred women with term pregnancies referred for induction of labour with Bishop score less than 6 were randomly allocated to receive either 40 mg IMN tablet vaginally (n=100) or 0.5 mg PGE2 gel intracervically (n=100).
Adverse effects, progress, and outcomes of labour were assessed.
Results.
PGE2 group had significantly higher postripening mean Bishop score, shorter time from start of medication to vaginal delivery (13.37 ± 10.67 hours versus 30.78 ± 17.29 hours), and shorter labour-delivery interval compared to IMN group (4.53 ± 3.97 hours versus 7.34 ± 5.51 hours).
However, PGE2 group also had significantly higher incidence of uterine tachysystole (15%) and N-RFH (11%) compared to none in IMN group, as well as higher caesarean section rate (27% versus 17%).
Conclusions.
Cervical ripening with IMN was less effective than PGE2 but resulted in fewer adverse effects and was safer especially in high risk pregnancies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Agarwal, Kavita& Batra, Achla& Batra, Aruna& Aggarwal, Abha. 2014. Randomized Comparison of Isosorbide Mononitrate and PGE2 Gel for Cervical Ripening at Term including High Risk Pregnancy. International Journal of Reproductive Medicine،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-449494
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Agarwal, Kavita…[et al.]. Randomized Comparison of Isosorbide Mononitrate and PGE2 Gel for Cervical Ripening at Term including High Risk Pregnancy. International Journal of Reproductive Medicine No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-449494
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Agarwal, Kavita& Batra, Achla& Batra, Aruna& Aggarwal, Abha. Randomized Comparison of Isosorbide Mononitrate and PGE2 Gel for Cervical Ripening at Term including High Risk Pregnancy. International Journal of Reproductive Medicine. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-449494
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-449494
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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