Insulin Sensitivity and Beta-Cell Function Are Associated with Arterial Stiffness in Individuals without Hypertension
المؤلفون المشاركون
Huang, Xiaoping
Yang, Tao
Fu, Qi
Shi, Yun
Duan, Yu
Wang, Zhixiao
Mao, Jia
Zhu, Zhenxin
Meng, Chuchen
Cao, Mengdie
Sun, Min
Tang, Wei
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-02-26
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Aim.
We investigated the relationship between brachial-ankle pulse wave velocity (baPWV) and glucose levels, insulin sensitivity, and beta-cell function in Chinese individuals with or without hypertension.
Methods.
We recruited 3137 nondiabetic individuals whose age, body mass index (BMI), glucose levels, blood pressure (BP), lipids, hemoglobin A1C (HbA1c), baPWV, and insulin levels were measured.
Results.
In normotensive group, 2 h glucose levels (β=0.046, P<0.001) associated with baPWV, showed a significant increase in patients with NG as compared to those with DM (P=0.032).
The hypertensive group showed no such differences.
The Matsuda index (β=0.114, P<0.001) and HOMA-β (β=0.045, P<0.001) were negatively correlated with baPWV while lnHOMA-IR (β=0.196, P=0.076) and the Quantitative Insulin Sensitivity Check Index (QUICKI) (β=0.226, P=0.046) showed a borderline negative correlation.
BaPWV significantly decreased (P=0.032) with an increase in insulin sensitivity in individuals with both normal BP and glucose tolerance.
Conclusions.
BaPWV was significantly associated with 2 h glucose levels, insulin sensitivity and beta-cell function in normotensive population, whereas in hypertensive individuals, BP was the dominant factor influencing arterial stiffness.
Individuals with abnormal insulin sensitivity in the absence of diabetes and hypertension are also at an increased risk of arterial stiffness.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Meng, Chuchen& Sun, Min& Wang, Zhixiao& Fu, Qi& Cao, Mengdie& Zhu, Zhenxin…[et al.]. 2013. Insulin Sensitivity and Beta-Cell Function Are Associated with Arterial Stiffness in Individuals without Hypertension. Journal of Diabetes Research،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-449899
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Meng, Chuchen…[et al.]. Insulin Sensitivity and Beta-Cell Function Are Associated with Arterial Stiffness in Individuals without Hypertension. Journal of Diabetes Research No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-449899
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Meng, Chuchen& Sun, Min& Wang, Zhixiao& Fu, Qi& Cao, Mengdie& Zhu, Zhenxin…[et al.]. Insulin Sensitivity and Beta-Cell Function Are Associated with Arterial Stiffness in Individuals without Hypertension. Journal of Diabetes Research. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-449899
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-449899
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر