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Investigation of Anti-Toxocara Antibodies in Epileptic Patients and Comparison of Two Methods : ELISA and Western Blotting
المؤلفون المشاركون
Bahrami, Parviz
Firoozeh, Farzaneh
Sadjjadi, Seyed Mahmoud
Zibaei, Mohammad
المصدر
Epilepsy Research and Treatment
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-04-22
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
The relationship between Toxocara infection and epilepsy was previously demonstrated by several case-control studies and case reports.
These previous studies were often based on the enzyme-linked immunosorbent assay (ELISA) using Toxocara excretory-secretory antigens, which are not specific due to cross-reactivity with other parasitic infections such as ascariasis, trichuriasis, and anisakiasis.
An immunoblot analysis is highly specific and can detect low levels of Toxocara antibodies.
Therefore, this assay may be useful in the identification of toxocariasis in epileptic patients.
We examined patients who had epilepsy and healthy subjects for seropositivity for Toxocara infection by ELISA and Western blotting.
Out of 85 epileptic patients, 10 (11.8%) and 3 (3.5%) persons exhibited Toxocara immunoglobulin G (IgG) antibodies responses by ELISA and by both techniques, respectively.
Moreover, in the healthy group (n=85), 3 (3.5%) persons were positive by ELISA, but none was detected by Western blotting.
This study indicates that Toxocara infection is a risk factor for epilepsy in Iran.
These findings strongly suggest the need to perform Western blotting immunodiagnosis, as well as the ELISA using Toxocara excretory-secretory antigens, to improve diagnosis of human toxocariasis in patients with epilepsy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zibaei, Mohammad& Firoozeh, Farzaneh& Bahrami, Parviz& Sadjjadi, Seyed Mahmoud. 2013. Investigation of Anti-Toxocara Antibodies in Epileptic Patients and Comparison of Two Methods : ELISA and Western Blotting. Epilepsy Research and Treatment،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-450305
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zibaei, Mohammad…[et al.]. Investigation of Anti-Toxocara Antibodies in Epileptic Patients and Comparison of Two Methods : ELISA and Western Blotting. Epilepsy Research and Treatment No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-450305
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zibaei, Mohammad& Firoozeh, Farzaneh& Bahrami, Parviz& Sadjjadi, Seyed Mahmoud. Investigation of Anti-Toxocara Antibodies in Epileptic Patients and Comparison of Two Methods : ELISA and Western Blotting. Epilepsy Research and Treatment. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-450305
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-450305
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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