The Impact of Demographic Characteristics and Lifestyle in the Distribution of Cystatin C Values in a Healthy Greek Adult Population

الملخص EN

Background.

The aim of the present study was to examine sources of variation for serum cystatin C in a healthy Greek population.

Methods.

Cystatin C together with basic clinical chemistry tests was measured in a total of 490 adults (46±16 yrs, 40% males) who underwent an annual health check.

Demographic, anthropometric, and lifestyle characteristics were recorded.

Results.

Higher values of cystatin C were observed among males (P=.04), participants aged over 65 years (P<.001), current smokers (P=.001) and overweight/obese participants (P=.03).

On the contrary, alcohol consumption and physical activity seemed to have no influence on cystatin C levels (P=.61; P=.95, resp.).

Conclusions.

In interpreting serum cystatin C values in a healthy adult population, age, gender, Body Mass Index, and cigarette smoking need to be considered, and determination of reference ranges among distinct subpopulations seem to be prudent.