Oncologic Outcomes of Surgery in T3 Prostate Cancer : Experience of a Single Tertiary Center
المؤلفون المشاركون
Smailyte, G.
Milonas, D.
Jievaltas, M.
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-12-19
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Aim.
The aim of this study is to present the oncologic outcomes and to determine the prognostic factors of overall survival (OS), cancer-specific survival (CSS), disease-progression-free survival (DPFS), and biochemical-progression-free survival (BPFS) after surgery for pT3 prostate cancer (PCa).
Methods.
Between 2002 and 2007, a pT3 stage after radical prostatectomy was detected in 182 patients at our institution.
The Kaplan-Meier analysis was used to calculate OS, CSS, DPFS, and BPFS.
Cox regression was used to identify predictive factors of survival.
Results.
pT3a was detected in 126 (69%) and pT3b in 56 (31%) of cases.
Five-year OS, CSS, DPFS, and BPFS rates were 90.7%, 94%, 91.8%, and 48.4%, respectively.
Survival was significantly different when comparing pT3a to pT3b groups.
The 5-year OS, CSS, DPFS, and BPFS were 96% versus 72%, 98% versus 77%, 97.3% versus 79.3%, and 60% versus 24.2%, respectively.
Specimen Gleason score was the most significant predictor of OS, CSS, DPFS, and BPFS.
The risk of death increased up to 3-fold when a Gleason score 8–10 was present at the final pathology.
Conclusions.
Radical prostatectomy may offer very good CSS, OS, DPFS, and BPFS rates in pT3a PCa.
However, outcomes in patients with pT3b or specimen Gleason ≥8 were significantly worse, suggesting the need for multimodality treatment in those cases.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Milonas, D.& Smailyte, G.& Jievaltas, M.. 2011. Oncologic Outcomes of Surgery in T3 Prostate Cancer : Experience of a Single Tertiary Center. Advances in Urology،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-450999
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Milonas, D.…[et al.]. Oncologic Outcomes of Surgery in T3 Prostate Cancer : Experience of a Single Tertiary Center. Advances in Urology No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-450999
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Milonas, D.& Smailyte, G.& Jievaltas, M.. Oncologic Outcomes of Surgery in T3 Prostate Cancer : Experience of a Single Tertiary Center. Advances in Urology. 2011. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-450999
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-450999
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر