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Histologic Changes of Implanted Gore Bio-A in an Experimental Animal Model
المؤلفون المشاركون
Park, Tae Hwan
Yeo, Kwan Koo
Park, Jin Hyuk
Seo, Sang Won
Kim, June-kyu
Chang, Choong Hyun
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-21
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Gore Bio-A has been reported to be an ideal synthetic bioabsorbable scaffold material for hernia repair.
The purpose of this study was to determine the effectiveness of Gore Bio-A in soft tissue augmentation.
Six New Zealand white rabbits were used in the study.
Five subcutaneous pockets were created on the back of the rabbit, and 20×20 mm sized square shaped Gore Bio-A sheets, each 1.5 mm, 3 mm, 4.5 mm, 6 mm, and 7.5 mm in thickness, were implanted into each pocket (1 layer to 5 layers).
To analyze the morphologic and histologic changes, the implants were harvested 1, 3, and 6 months after implantation.
Following the gross analysis, absorption rate was accelerated with increased implant duration and decreased thickness.
Histological analysis of the implants demonstrated progressive neovascularization, fibroblast infiltration, and neocollagenation over time.
Six months after implantation, Gore Bio-A was almost absorbed and degenerated, not maintaining its volume.
Based on this study, Gore Bio-A was revealed as a biocompatible material; however, it is not suitable for soft tissue augmentation because it is absorbed in the process of changing into soft tissue without maintaining its own volume.
Therefore, this material is incomplete and needs more study to overcome this limitation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yeo, Kwan Koo& Park, Tae Hwan& Park, Jin Hyuk& Chang, Choong Hyun& Kim, June-kyu& Seo, Sang Won. 2014. Histologic Changes of Implanted Gore Bio-A in an Experimental Animal Model. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-451267
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yeo, Kwan Koo…[et al.]. Histologic Changes of Implanted Gore Bio-A in an Experimental Animal Model. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-451267
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yeo, Kwan Koo& Park, Tae Hwan& Park, Jin Hyuk& Chang, Choong Hyun& Kim, June-kyu& Seo, Sang Won. Histologic Changes of Implanted Gore Bio-A in an Experimental Animal Model. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-451267
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-451267
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