The Korean Mistletoe (Viscum album coloratum) Extract Has an Antiobesity Effect and Protects against Hepatic Steatosis in Mice with High-Fat Diet-Induced Obesity
المؤلفون المشاركون
Jeong, Ju Seong
Kim, Kyong-Tai
Kim, In-Bo
Kim, Jong-Bae
Do, Myoung-Sool
Jung, Seung-Pil
Kim, Kwang-Soo
Lee, Jung-Han
Kim, Yu-Hee
Jung, Hoe-Yune
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-07-11
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
This study investigates the inhibitory effects of Korean mistletoe extract (KME) on adipogenic factors in 3T3-L1 cells and obesity and nonalcoholic fatty liver disease (NAFLD) in mice fed a high-fat diet.
Male C57Bl/6 mice fed a high-fat diet were treated with KME (3 g/kg/day) for 15 weeks for the antiobesity and NAFLD experiments.
Body weight and daily food intake were measured regularly during the experimental period.
The epididymal pad was measured and liver histology was observed.
The effects of KME on thermogenesis and endurance capacity were measured.
The effects of KME on adipogenic factors were examined in 3T3-L1 cells.
Body and epididymal fat pad weights were reduced in KME-treated mice, and histological examination showed an amelioration of fatty liver in KME-treated mice, without an effect on food consumption.
KME potently induces mitochondrial activity by activating thermogenesis and improving endurance capacity.
KME also inhibited adipogenic factors in vitro.
These results demonstrate the inhibitory effects of KME on obesity and NAFLD in mice fed a high-fat diet.
The effects appear to be mediated through an enhanced mitochondrial activity.
Therefore, KME may be an effective therapeutic candidate for treating obesity and fatty liver caused by a high-fat diet.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jung, Hoe-Yune& Kim, Yu-Hee& Kim, In-Bo& Jeong, Ju Seong& Lee, Jung-Han& Do, Myoung-Sool…[et al.]. 2013. The Korean Mistletoe (Viscum album coloratum) Extract Has an Antiobesity Effect and Protects against Hepatic Steatosis in Mice with High-Fat Diet-Induced Obesity. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-451296
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jung, Hoe-Yune…[et al.]. The Korean Mistletoe (Viscum album coloratum) Extract Has an Antiobesity Effect and Protects against Hepatic Steatosis in Mice with High-Fat Diet-Induced Obesity. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-451296
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jung, Hoe-Yune& Kim, Yu-Hee& Kim, In-Bo& Jeong, Ju Seong& Lee, Jung-Han& Do, Myoung-Sool…[et al.]. The Korean Mistletoe (Viscum album coloratum) Extract Has an Antiobesity Effect and Protects against Hepatic Steatosis in Mice with High-Fat Diet-Induced Obesity. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-451296
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-451296
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر