![](/images/graphics-bg.png)
Experimental and Modeling Study of Collagen Scaffolds with the Effects of Crosslinking and Fiber Alignment
المؤلفون المشاركون
Xu, Bin
Zhang, Yanhang
Chow, Ming-Jay
المصدر
International Journal of Biomaterials
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-08-23
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Collagen type I scaffolds are commonly used due to its abundance, biocompatibility, and ubiquity.
Most applications require the scaffolds to operate under mechanical stresses.
Therefore understanding and being able to control the structural-functional integrity of collagen scaffolds becomes crucial.
Using a combined experimental and modeling approach, we studied the structure and function of Type I collagen gel with the effects of spatial fiber alignment and crosslinking.
Aligned collagen scaffolds were created through the flow of magnetic particles enmeshed in collagen fibrils to mimic the anisotropy seen in native tissue.
Inter- and intra- molecular crosslinking was modified chemically with Genipin to further improve the stiffness of collagen scaffolds.
The anisotropic mechanical properties of collagen scaffolds were characterized using a planar biaxial tensile tester and parallel plate rheometer.
The tangent stiffness from biaxial tensile test is two to three orders of magnitude higher than the storage moduli from rheological measurements.
The biphasic nature of collagen gel was discussed and used to explain the mechanical behavior of collagen scaffolds under different types of mechanical tests.
An anisotropic hyperelastic constitutive model was used to capture the characteristics of the stress-strain behavior exhibited by collagen scaffolds.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Xu, Bin& Chow, Ming-Jay& Zhang, Yanhang. 2011. Experimental and Modeling Study of Collagen Scaffolds with the Effects of Crosslinking and Fiber Alignment. International Journal of Biomaterials،Vol. 2011, no. 2011, pp.1-12.
https://search.emarefa.net/detail/BIM-451649
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Xu, Bin…[et al.]. Experimental and Modeling Study of Collagen Scaffolds with the Effects of Crosslinking and Fiber Alignment. International Journal of Biomaterials No. 2011 (2011), pp.1-12.
https://search.emarefa.net/detail/BIM-451649
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Xu, Bin& Chow, Ming-Jay& Zhang, Yanhang. Experimental and Modeling Study of Collagen Scaffolds with the Effects of Crosslinking and Fiber Alignment. International Journal of Biomaterials. 2011. Vol. 2011, no. 2011, pp.1-12.
https://search.emarefa.net/detail/BIM-451649
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-451649
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)