The Potential Benefits and Adverse Effects of Phytic Acid Supplement in Streptozotocin-Induced Diabetic Rats
المؤلفون المشاركون
Olumese, F. E.
Ejilemele, A.
Budiaman, A.
Omoruyi, F. O.
Okorodudu, A. O.
Eng, Y.
Hoesel, J. L.
المصدر
Advances in Pharmacological Sciences
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-22
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
In this study, the effect of phytic acid supplement on streptozotocin-induced diabetic rats was investigated.
Diabetic rats were fed rodent chow with or without phytic acid supplementation for thirty days.
Blood and organ samples were collected for assays.
The average food intake was the highest and the body weight gain was the lowest in the group fed phytic acid supplement compared to the diabetic and normal control groups.
There was a downward trend in intestinal amylase activity in the group fed phytic acid supplement compared to the other groups.
The spike in random blood glucose was the lowest in the same group.
We noted reduced serum triglycerides and increased total cholesterol and HDL cholesterol levels in the group fed phytic acid supplement.
Serum alkaline phosphatase and alanine amino transferase activities were significantly (P<0.05) increased by phytic acid supplementation.
Systemic IL-1β level was significantly (P<0.05) elevated in the diabetic control and supplement treated groups.
The liver lipogenic enzyme activities were not significantly altered among the groups.
These results suggest that phytic acid supplementation may be beneficial in the management of diabetes mellitus.
The observed adverse effect on the liver may be due to the combined effect of streptozotocin-induced diabetes and phytic acid supplementation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Omoruyi, F. O.& Budiaman, A.& Eng, Y.& Olumese, F. E.& Hoesel, J. L.& Ejilemele, A.…[et al.]. 2013. The Potential Benefits and Adverse Effects of Phytic Acid Supplement in Streptozotocin-Induced Diabetic Rats. Advances in Pharmacological Sciences،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-451658
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Omoruyi, F. O.…[et al.]. The Potential Benefits and Adverse Effects of Phytic Acid Supplement in Streptozotocin-Induced Diabetic Rats. Advances in Pharmacological Sciences No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-451658
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Omoruyi, F. O.& Budiaman, A.& Eng, Y.& Olumese, F. E.& Hoesel, J. L.& Ejilemele, A.…[et al.]. The Potential Benefits and Adverse Effects of Phytic Acid Supplement in Streptozotocin-Induced Diabetic Rats. Advances in Pharmacological Sciences. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-451658
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-451658
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر