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Scaffolds for Growth Factor Delivery as Applied to Bone Tissue Engineering
المؤلفون المشاركون
Ann Woodruff, Maria
Blackwood, Keith A.
Dargaville, Tim R.
Bock, Nathalie
المصدر
International Journal of Polymer Science
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-25، 25ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-11-11
دولة النشر
مصر
عدد الصفحات
25
التخصصات الرئيسية
الملخص EN
There remains a substantial shortfall in the treatment of severe skeletal injuries.
The current gold standard of autologous bone grafting from the same patient has many undesirable side effects associated such as donor site morbidity.
Tissue engineering seeks to offer a solution to this problem.
The primary requirements for tissue-engineered scaffolds have already been well established, and many materials, such as polyesters, present themselves as potential candidates for bone defects; they have comparable structural features, but they often lack the required osteoconductivity to promote adequate bone regeneration.
By combining these materials with biological growth factors, which promote the infiltration of cells into the scaffold as well as the differentiation into the specific cell and tissue type, it is possible to increase the formation of new bone.
However due to the cost and potential complications associated with growth factors, controlling the rate of release is an important design consideration when developing new bone tissue engineering strategies.
This paper will cover recent research in the area of encapsulation and release of growth factors within a variety of different polymeric scaffolds.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Blackwood, Keith A.& Bock, Nathalie& Dargaville, Tim R.& Ann Woodruff, Maria. 2012. Scaffolds for Growth Factor Delivery as Applied to Bone Tissue Engineering. International Journal of Polymer Science،Vol. 2012, no. 2012, pp.1-25.
https://search.emarefa.net/detail/BIM-451897
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Blackwood, Keith A.…[et al.]. Scaffolds for Growth Factor Delivery as Applied to Bone Tissue Engineering. International Journal of Polymer Science No. 2012 (2012), pp.1-25.
https://search.emarefa.net/detail/BIM-451897
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Blackwood, Keith A.& Bock, Nathalie& Dargaville, Tim R.& Ann Woodruff, Maria. Scaffolds for Growth Factor Delivery as Applied to Bone Tissue Engineering. International Journal of Polymer Science. 2012. Vol. 2012, no. 2012, pp.1-25.
https://search.emarefa.net/detail/BIM-451897
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-451897
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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