A Case of Severe Hydroxychloroquine-Induced Retinal Toxicity in a Patient with Recent Onset of Renal Impairment : A Review of the Literature on the Use of Hydroxychloroquine in Renal Impairment
المؤلفون المشاركون
Tailor, Rajen
Good, Peter
Scott, Robert A. H.
Elaraoud, Ibrahim
Hope-Ross, Monique
المصدر
Case Reports in Ophthalmological Medicine
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-3، 3ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-12-09
دولة النشر
مصر
عدد الصفحات
3
التخصصات الرئيسية
الملخص EN
We present a case of a 67-year-old female who presented with a twelve-month history of progressive blurred vision in both eyes.
The patient was on hydroxychloroquine 200 mg twice a day for eight years for the treatment of scarring alopecia.
Two years prior to presenting, the patient was found to have chronic kidney disease stage 3 secondary to hypertension.
Examination revealed bilateral reduced visual acuities with attenuated arterioles and pigmentary changes on retinal assessment.
Goldmann visual fields showed grossly constricted fields in both eyes.
The patient was diagnosed with retinal toxicity secondary to hydroxychloroquine probably potentiated by renal impairment.
Risk factors for retinal toxicity secondary to hydroxychloroquine can be broadly divided into dose-related and patient-related factors.
Our patient developed severe retinal toxicity despite being on the recommended daily dose (400 mg per day).
Although retinal toxicity at this dose has been documented, the development of renal impairment without dose adjustment or close monitoring of visual function is likely to have potentiated retinal toxicity.
This case highlights the need to monitor renal function in patients on hydroxychloroquine.
Should renal impairment develop, either the drug should be stopped or the dose reduced with close monitoring of visual function by an ophthalmologist.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tailor, Rajen& Elaraoud, Ibrahim& Good, Peter& Hope-Ross, Monique& Scott, Robert A. H.. 2012. A Case of Severe Hydroxychloroquine-Induced Retinal Toxicity in a Patient with Recent Onset of Renal Impairment : A Review of the Literature on the Use of Hydroxychloroquine in Renal Impairment. Case Reports in Ophthalmological Medicine،Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-452527
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tailor, Rajen…[et al.]. A Case of Severe Hydroxychloroquine-Induced Retinal Toxicity in a Patient with Recent Onset of Renal Impairment : A Review of the Literature on the Use of Hydroxychloroquine in Renal Impairment. Case Reports in Ophthalmological Medicine No. 2012 (2012), pp.1-3.
https://search.emarefa.net/detail/BIM-452527
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tailor, Rajen& Elaraoud, Ibrahim& Good, Peter& Hope-Ross, Monique& Scott, Robert A. H.. A Case of Severe Hydroxychloroquine-Induced Retinal Toxicity in a Patient with Recent Onset of Renal Impairment : A Review of the Literature on the Use of Hydroxychloroquine in Renal Impairment. Case Reports in Ophthalmological Medicine. 2012. Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-452527
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-452527
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر