Transarterial Chemoembolization for the Treatment of Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis : Prognostic Factors in a Single-Center Study of 188 Patients
المؤلفون المشاركون
Fan, Daiming
Liu, Lei
Bai, Wei
He, Chuangye
Zhang, Cheng
Yin, Zhanxin
Chen, Hui
Han, Guohong
Guo, Wengang
Zhao, Yan
Qi, Xingshun
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-04-08
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Transarterial chemoembolization (TACE) could achieve a better survival benefit than conservative treatment for advanced hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT).
In this retrospective study, all HCC patients with Child-Pugh score <7 and PVTT who were consecutively admitted to our center between January 2006 and June 2012 and underwent TACE were enrolled.
The efficacy and safety of TACE were analyzed.
Prognostic factors were determined by Cox regression analysis.
Of the 188 patients included, 89% had hepatitis B virus infection, 100% were at Barcelona Clinic Liver Cancer stage C, and 81% (n=152) and 19% (n=36) were at Child-Pugh classes A and B, respectively.
The incidence of procedure-related complications was 88%.
No procedure-related death was found.
The median overall survival was 6.1 months.
Type of PVTT (hazard ratio [HR] = 2.806), number of tumor lesions (HR = 2.288), Child-Pugh class (HR = 2.981), and presence of metastasis (HR = 1.909) were the independent predictors of survival.
In conclusion, TACE could be selectively used for the treatment of advanced HCC with PVTT.
But a high rate of postoperative adverse events should not be undermined in spite of no procedure-related death.
Preoperative type of PVTT, number of tumor lesions, Child-Pugh class, and metastasis could predict the prognosis of these patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liu, Lei& Zhang, Cheng& Zhao, Yan& Qi, Xingshun& Chen, Hui& Bai, Wei…[et al.]. 2014. Transarterial Chemoembolization for the Treatment of Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis : Prognostic Factors in a Single-Center Study of 188 Patients. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-453497
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liu, Lei…[et al.]. Transarterial Chemoembolization for the Treatment of Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis : Prognostic Factors in a Single-Center Study of 188 Patients. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-453497
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liu, Lei& Zhang, Cheng& Zhao, Yan& Qi, Xingshun& Chen, Hui& Bai, Wei…[et al.]. Transarterial Chemoembolization for the Treatment of Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis : Prognostic Factors in a Single-Center Study of 188 Patients. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-453497
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-453497
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر