![](/images/graphics-bg.png)
Immunophenotype Expressions and Cytokine Profiles of Influenza A H1N1 Virus Infection in Pediatric Patients in 2009
المؤلفون المشاركون
Wang, Shih-Min
Hu, Yu-Shiang
Lin, Yee-Shin
Ho, Tzong-Shiann
Liao, Yu-Ting
Shen, Ching-Fen
Liu, Ching-Chuan
Wang, Jen-Ren
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-02-18
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
A novel swine-origin influenza A H1N1 virus (S-OIV) caused human infection and acute respiratory illness in 2009, resulting in an influenza pandemic.
Objectives.
This study characterized the immune responses of S-OIV infection in pediatric patients at risk of pulmonary complications.
Methods.
All enrolled pediatric patients were confirmed virologically for S-OIV infection in 2009-2010, prospectively.
Changes in cellular immunophenotypes were analyzed using flow cytometry.
Plasma cytokine levels associated with S-OIV infection by pulmonary and without pulmonary complications were measured using cytokine cytometric bead assay kits.
Results.
A total of 85 patients with a mean age of 10.3 years were recruited.
The level of C-reactive protein (CRP) was high in patients exhibiting pulmonary complications.
The percentage of cellular immunophenotypes did not change between patients with and without pulmonary complications.
The absolute numbers of peripheral blood mononuclear cells (PBMC), CD3, CD8, and CD16CD56 decreased with acute S-OIV pulmonary complications.
Acute influenza infection with pulmonary complications was associated with high plasma concentrations of IL-1β, IL-6, IL-12, and IFN-γ.
Conclusion.
Immunophenotype studies have reported variability in immune response to the severity of S-OIV infections.
Acute phase cytokine profiles of the 2009 S-OIV infection might have contributed to the pathogenesis of the pulmonary complications.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Shih-Min& Liao, Yu-Ting& Hu, Yu-Shiang& Ho, Tzong-Shiann& Shen, Ching-Fen& Wang, Jen-Ren…[et al.]. 2014. Immunophenotype Expressions and Cytokine Profiles of Influenza A H1N1 Virus Infection in Pediatric Patients in 2009. Disease Markers،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-453603
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Shih-Min…[et al.]. Immunophenotype Expressions and Cytokine Profiles of Influenza A H1N1 Virus Infection in Pediatric Patients in 2009. Disease Markers No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-453603
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Shih-Min& Liao, Yu-Ting& Hu, Yu-Shiang& Ho, Tzong-Shiann& Shen, Ching-Fen& Wang, Jen-Ren…[et al.]. Immunophenotype Expressions and Cytokine Profiles of Influenza A H1N1 Virus Infection in Pediatric Patients in 2009. Disease Markers. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-453603
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-453603
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)