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Antifungal Activity of Brazilian Propolis Microparticles against Yeasts Isolated from Vulvovaginal Candidiasis
المؤلفون المشاركون
Consolaro, Marcia Edilaine Lopes
Dota, Kelen Fátima Dalben
Bruschi, Marcos Luciano
Svidzinski, Terezinha Inez Estivalet
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-03-09
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Propolis, a resinous compound produced by Apis mellifera L.
bees, is known to possess a variety of biological activities and is applied in the therapy of various infectious diseases.
The aim of this study was to evaluate the in vitro antifungal activity of propolis ethanol extract (PE) and propolis microparticles (PMs) obtained from a sample of Brazilian propolis against clinical yeast isolates of importance in the vulvovaginal candidiasis (VVC).
PE was used to prepare the microparticles.
Yeast isolates (n=89), obtained from vaginal exudates of patients with VVC, were exposed to the PE and the PMs.
Moreover, the main antifungal drugs used in the treatment of VVC (Fluconazole, Voriconazole, Itraconazole, Ketoconazole, Miconazole and Amphotericin B) were also tested.
Minimum inhibitory concentration (MIC) was determined according to the standard broth microdilution method.
Some Candida albicans isolates showed resistance or dose-dependent susceptibility for the azolic drugs and Amphotericin B.
Non-C.
albicans isolates showed more resistance and dose-dependent susceptibility for the azolic drugs than C.
albicans.
However, all of them were sensitive or dose-dependent susceptible for Amphotericin B.
All yeasts were inhibited by PE and PMs, with small variation, independent of the species of yeast.
The overall results provided important information for the potential application of PMs in the therapy of VVC and the possible prevention of the occurrence of new symptomatic episodes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Dota, Kelen Fátima Dalben& Consolaro, Marcia Edilaine Lopes& Svidzinski, Terezinha Inez Estivalet& Bruschi, Marcos Luciano. 2011. Antifungal Activity of Brazilian Propolis Microparticles against Yeasts Isolated from Vulvovaginal Candidiasis. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-454050
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Dota, Kelen Fátima Dalben…[et al.]. Antifungal Activity of Brazilian Propolis Microparticles against Yeasts Isolated from Vulvovaginal Candidiasis. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-454050
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Dota, Kelen Fátima Dalben& Consolaro, Marcia Edilaine Lopes& Svidzinski, Terezinha Inez Estivalet& Bruschi, Marcos Luciano. Antifungal Activity of Brazilian Propolis Microparticles against Yeasts Isolated from Vulvovaginal Candidiasis. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-454050
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-454050
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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