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Association of Active Human Herpesvirus-6, -7 and Parvovirus B19 Infection with Clinical Outcomes in Patients with Myalgic EncephalomyelitisChronic Fatigue Syndrome
المؤلفون المشاركون
Logina, Inara
Murovska, Modra
Rasa, Santa
Chapenko, Svetlana
Sultanova, Alina
Krumina, Angelika
Chistjakovs, Maksims
Viksna, Ludmila
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-08-13
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Frequency of active human herpesvirus-6, -7 (HHV-6, HHV-7) and parvovirus B19 (B19) infection/coinfection and its association with clinical course of ME/CFS was evaluated.
108 ME/CFS patients and 90 practically healthy persons were enrolled in the study.
Viral genomic sequences were detected by PCR, virus-specific antibodies and cytokine levels—by ELISA, HHV-6 variants—by restriction analysis.
Active viral infection including concurrent infection was found in 64.8% (70/108) of patients and in 13.3% (12/90) of practically healthy persons.
Increase in peripheral blood leukocyte DNA HHV-6 load as well as in proinflammatory cytokines' levels was detected in patients during active viral infection.
Definite relationship was observed between active betaherpesvirus infection and subfebrility, lymphadenopathy and malaise after exertion, and between active B19 infection and multijoint pain.
Neuropsychological disturbances were detected in all patients.
The manifestation of symptoms was of more frequent occurrence in patients with concurrent infection.
The high rate of active HHV-6, HHV-7 and B19 infection/coinfection with the simultaneous increase in plasma proinflammatory cytokines' level as well as the association between active viral infection and distinctive types of clinical symptoms shows necessity of simultaneous study of these viral infections for identification of possible subsets of ME/CFS.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chapenko, Svetlana& Krumina, Angelika& Logina, Inara& Rasa, Santa& Chistjakovs, Maksims& Sultanova, Alina…[et al.]. 2012. Association of Active Human Herpesvirus-6, -7 and Parvovirus B19 Infection with Clinical Outcomes in Patients with Myalgic EncephalomyelitisChronic Fatigue Syndrome. Advances in Virology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-454311
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chapenko, Svetlana…[et al.]. Association of Active Human Herpesvirus-6, -7 and Parvovirus B19 Infection with Clinical Outcomes in Patients with Myalgic EncephalomyelitisChronic Fatigue Syndrome. Advances in Virology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-454311
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chapenko, Svetlana& Krumina, Angelika& Logina, Inara& Rasa, Santa& Chistjakovs, Maksims& Sultanova, Alina…[et al.]. Association of Active Human Herpesvirus-6, -7 and Parvovirus B19 Infection with Clinical Outcomes in Patients with Myalgic EncephalomyelitisChronic Fatigue Syndrome. Advances in Virology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-454311
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-454311
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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