Chlamydia trachomatis Serology in Women with and without Ovarian Cancer

الملخص EN

Pelvic inflammation has been implicated in the genesis of ovarian cancer.

We conducted serologic measurements of Chlamydia trachomatis antibodies as a surrogate marker of chlamydial pelvic inflammatory disease.

Women with ovarian cancer (n=521) and population-based controls (n=766) were tested.

IgG antibodies to serovar D of chlamydia elementary bodies (EBs) were detected using an ELISA assay.

The odds of having ovarian cancer among women with the highest titers (≥0.40 OD units) were 0.6 (95% CI 0.4–0.9).

These data do not support our earlier finding of elevated titers for antibodies to C.

trachomatis among women with ovarian cancer.