Long-Term Effects of Maternal Deprivation on the Neuronal Soma Area in the Rat Neocortex
المؤلفون المشاركون
Filipović, Branislav
Radonjić, Vidosava
Radonjić, Nevena V.
Aleksić, Dubravka
Marković, Branka
Jevtić, Gordana
Petronijević, Nataša
Aksić, Milan
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-08
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Early separation of rat pups from their mothers (separatio a matrem) is considered and accepted as an animal model of perinatal stress.
Adult rats, separated early postnatally from their mothers, are developing long-lasting changes in the brain and neuroendocrine system, corresponding to the findings observed in schizophrenia and affective disorders.
With the aim to investigate the morphological changes in this animal model we exposed 9-day-old (P9) Wistar rats to a 24 h maternal deprivation (MD).
At young adult age rats were sacrificed for morphometric analysis and their brains were compared with the control group bred under the same conditions, but without MD.
Rats exposed to MD had a 28% smaller cell soma area in the prefrontal cortex (PFCX), 30% in retrosplenial cortex (RSCX), and 15% in motor cortex (MCX) compared to the controls.
No difference was observed in the expression of glial fibrillary acidic protein in the neocortex of MD rats compared to the control group.
The results of this study demonstrate that stress in early life has a long-term effect on neuronal soma size in cingulate and retrosplenial cortex and is potentially interesting as these structures play an important role in cognition.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Aksić, Milan& Radonjić, Nevena V.& Aleksić, Dubravka& Jevtić, Gordana& Marković, Branka& Petronijević, Nataša…[et al.]. 2014. Long-Term Effects of Maternal Deprivation on the Neuronal Soma Area in the Rat Neocortex. BioMed Research International،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-456047
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Aksić, Milan…[et al.]. Long-Term Effects of Maternal Deprivation on the Neuronal Soma Area in the Rat Neocortex. BioMed Research International No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-456047
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Aksić, Milan& Radonjić, Nevena V.& Aleksić, Dubravka& Jevtić, Gordana& Marković, Branka& Petronijević, Nataša…[et al.]. Long-Term Effects of Maternal Deprivation on the Neuronal Soma Area in the Rat Neocortex. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-456047
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-456047
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر