![](/images/graphics-bg.png)
The Effect of Prophylactic Dexmedetomidine on Hemodynamic Disturbances to Double-Lumen Endotracheal Intubation : A Prospective, Randomized, Double-Blind, and Placebo-Controlled Trial
المؤلفون المشاركون
Pipanmekaporn, Tanyong
Lapisatepun, Worawut
Punjasawadwong, Yodying
Bunburaphong, Pavena
Charuluxananan, Somrat
المصدر
Anesthesiology Research and Practice
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-07-29
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
The purpose of this study was to determine the effect of dexmedetomidine on hemodynamic responses to DLT intubation compared to placebo and to assess the adverse effects related to dexmedetomidine.
Sixty patients were randomly allocated to receive 0.7 μg/kg dexmedetomidine (n=30) or normal saline (n=30) 10 minutes before general anesthesia.
Systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), and rate pressure product (RPP) between groups were recorded.
During intubation and 10 minutes afterward (T1-T10), the mean SBP, DBP, MAP, HR, and RPP in the control group were significantly higher than those in the dexmedetomidine group throughout the study period except at T1.
The mean differences of SBP, DBP, MAP, HR, and RPP were significantly higher in the control group, with the value of 15.2 mmHg, 10.5 mmHg, 14 mmHg, 10.5 beats per minute, and 2,462.8 mmHg min−1.
Four patients in the dexmedetomidine group and 1 patient in the control group developed hypotension, while 2 patients in the dexmedetomidine group had bradycardia.
Prophylactic dexmedetomidine can attenuate the hemodynamic responses to laryngoscopy and DLT intubation with minimal adverse effects.
This trial is registered with ClinicalTrials.gov NCT01289769.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pipanmekaporn, Tanyong& Punjasawadwong, Yodying& Charuluxananan, Somrat& Lapisatepun, Worawut& Bunburaphong, Pavena. 2013. The Effect of Prophylactic Dexmedetomidine on Hemodynamic Disturbances to Double-Lumen Endotracheal Intubation : A Prospective, Randomized, Double-Blind, and Placebo-Controlled Trial. Anesthesiology Research and Practice،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-456121
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pipanmekaporn, Tanyong…[et al.]. The Effect of Prophylactic Dexmedetomidine on Hemodynamic Disturbances to Double-Lumen Endotracheal Intubation : A Prospective, Randomized, Double-Blind, and Placebo-Controlled Trial. Anesthesiology Research and Practice No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-456121
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pipanmekaporn, Tanyong& Punjasawadwong, Yodying& Charuluxananan, Somrat& Lapisatepun, Worawut& Bunburaphong, Pavena. The Effect of Prophylactic Dexmedetomidine on Hemodynamic Disturbances to Double-Lumen Endotracheal Intubation : A Prospective, Randomized, Double-Blind, and Placebo-Controlled Trial. Anesthesiology Research and Practice. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-456121
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-456121
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)