Assessment of Some Inflammatory Biomarkers as Predictors of Outcome of Acute Respiratory Failure on Top of Chronic Obstructive Pulmonary Disease and Evaluation of the Role of Bacteria
المؤلفون المشاركون
El-Hoffy, Mohamed Mabrouk
Khalil, Yehia Mohamed
Abd-Elwahab, Nashwa Hassan
Degady, Akram Abd-Elmoneim
Baddour, Manal Mohammad
Shafiek, Hanaa Ahmed
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-06-21
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Objective.
To study the value of the inflammatory markers (interleukin-6 (IL-6), interleukin-8 (IL-8), and C-reactive protein (CRP)) in predicting the outcome of noninvasive ventilation (NIV) in the management of acute respiratory failure (ARF) on top of chronic obstructive pulmonary disease (COPD) and the role of bacteria in the systemic inflammation.
Methods.
Thirty three patients were subjected to standard treatment plus NIV, and accordingly, they were classified into responders and nonresponders.
Serum samples were collected for IL-6, IL-8, and CRP analysis.
Sputum samples were taken for microbiological evaluation.
Results.
A wide spectrum of bacteria was revealed; Gram-negative and atypical bacteria were the most common (31% and 28% resp.; single or copathogen).
IL-8 and dyspnea grade was significantly higher in the non-responder group (P=0.01 and 0.023 resp.).
IL-6 correlated positivity with the presence of infection and type of pathogen (P=0.038 and 0.034 resp.).
Gram-negative bacteria were associated with higher significant IL-6 in comparison between others (196.4±239.1 pg/dL; P=0.011) but insignificantly affected NIV outcome (P>0.05).
Conclusions.
High systemic inflammation could predict failure of NIV.
G-ve bacteria correlated with high IL-6 but did not affect the response to NIV.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shafiek, Hanaa Ahmed& Abd-Elwahab, Nashwa Hassan& Baddour, Manal Mohammad& El-Hoffy, Mohamed Mabrouk& Degady, Akram Abd-Elmoneim& Khalil, Yehia Mohamed. 2012. Assessment of Some Inflammatory Biomarkers as Predictors of Outcome of Acute Respiratory Failure on Top of Chronic Obstructive Pulmonary Disease and Evaluation of the Role of Bacteria. ISRN Microbiology،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-456586
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shafiek, Hanaa Ahmed…[et al.]. Assessment of Some Inflammatory Biomarkers as Predictors of Outcome of Acute Respiratory Failure on Top of Chronic Obstructive Pulmonary Disease and Evaluation of the Role of Bacteria. ISRN Microbiology No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-456586
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shafiek, Hanaa Ahmed& Abd-Elwahab, Nashwa Hassan& Baddour, Manal Mohammad& El-Hoffy, Mohamed Mabrouk& Degady, Akram Abd-Elmoneim& Khalil, Yehia Mohamed. Assessment of Some Inflammatory Biomarkers as Predictors of Outcome of Acute Respiratory Failure on Top of Chronic Obstructive Pulmonary Disease and Evaluation of the Role of Bacteria. ISRN Microbiology. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-456586
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-456586
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر