Antiangiogenic Therapy in the Treatment of Recurrent Medulloblastoma in the Adult : Case Report and Review of the Literature

الملخص EN

Medulloblastoma is a rare tumor in central nervous system, with an even rarer occurrence in adulthood.

The management of a recurrent disease is a medical challenge; chemotherapy has been used as the treatment of choice, while reirradiation has been employed in selected cases.

We report the case of a 51-year-old man with recurrent medulloblastoma.

He was treated with local reirradiation, chemotherapy, and antiangiogenic drug, with the latter giving the longer progression-free interval.

The aim of this report is to show that recurrent medulloblastoma in adults can be approached with a multimodality treatment and that antiangiogenic therapy should have a role in the management of this disease.