Frequent Genital HSV-2 Shedding among Women during Labor in Soweto, South Africa
المؤلفون المشاركون
Huang, Meei-Li
De Bruyn, Guy
Wald, Anna
Gray, Glenda
Perti, Tara
Magaret, Amalia
Velaphi, Sithembiso
Corey, Lawrence
Selke, Stacy
Nyati, Mandisa
المصدر
Infectious Diseases in Obstetrics and Gynecology
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-20
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Despite high herpes simplex virus type 2 (HSV-2) incidence and prevalence among women in Africa, we are unaware of published neonatal herpes reports.
To assess neonatal HSV transmission potential in South Africa, we investigated the frequency of the strongest risk factors: HSV acquisition in late pregnancy and HSV shedding during labor.
Methods.
Women admitted in early labor to a hospital in Soweto underwent HSV serologic testing and genital swab collection for HSV PCR.
HSV-2 seronegative women were assessed for seroconversion 4–6 weeks after delivery.
Results.
Of 390 women enrolled, 229 (58.7%) were HSV-2 seropositive.
Genital HSV-2 was detected in 17.2% of HSV-2 seropositive women, including 26 of 115 HIV-positive and 13 of 110 HIV-negative women (22.6% versus 11.8%; RR, 1.91; 95% CI, 1.04–3.53; P=0.038), but in none of 161 HSV-2 seronegative women.
Among the 91 HSV-2 seronegative women followed after delivery, none seroconverted.
Conclusions.
HSV-2 reactivation is common among South African women during labor, especially those with HIV coinfection.
To determine the epidemiology of neonatal herpes in South Africa and to investigate whether the lack of reported cases is due to alterations in immune control or HSV-2 virulence, studies evaluating acutely ill neonates for HSV and studies of maternal HSV-2 shedding patterns are needed.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Perti, Tara& Nyati, Mandisa& Gray, Glenda& De Bruyn, Guy& Selke, Stacy& Magaret, Amalia…[et al.]. 2014. Frequent Genital HSV-2 Shedding among Women during Labor in Soweto, South Africa. Infectious Diseases in Obstetrics and Gynecology،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-458063
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Perti, Tara…[et al.]. Frequent Genital HSV-2 Shedding among Women during Labor in Soweto, South Africa. Infectious Diseases in Obstetrics and Gynecology No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-458063
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Perti, Tara& Nyati, Mandisa& Gray, Glenda& De Bruyn, Guy& Selke, Stacy& Magaret, Amalia…[et al.]. Frequent Genital HSV-2 Shedding among Women during Labor in Soweto, South Africa. Infectious Diseases in Obstetrics and Gynecology. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-458063
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-458063
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر