Nutritional Biomarkers in Children and Adolescents with Beta-Thalassemia-Major : An Egyptian Center Experience
المؤلفون المشاركون
Abd El-Salam, Sanaa M.
Gharieb, Amal F.
Kamal, Naglaa M.
Azab, Seham F.
Sherief, Laila M.
El safy, Osama
Almalky, Mohamed A. A.
Morsy, Hemat M.
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-04-08
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background and Aim.
Trace elements and vitamins play a vital role in human body to perform its function properly.
Thalassemic patients are at risk of micronutrient deficiency.
This study estimated levels of vitamins A, C, E, B12, folic acid, total homocysteine (tHcy), and methylmalonic acid (MMA) along with trace elements, zinc, copper, and selenium in Beta-thalassemia-major patients.
Methods.
This study included 108 patients with Beta-thalassemia-major and 60 age and sex matched healthy children.
Serum levels of vitamin A, E, C, tHcy, and MMA were estimated by high pressure liquid chromatography while serum levels of folic acid and B12 were estimated by thin layer chromatography.
Serum zinc, copper, and selenium were determined by atomic absorption spectrometry.
Results.
There was a significant decrease of vitamins A, C, E, and B12 and trace elements zinc, copper, and selenium in thalassemic patients as compared to controls.
tHcy and MMA were significantly elevated in patients.
No significant correlations were found between the serum levels of the studied vitamins and trace elements as regards age, frequency of transfusion, duration of transfusion, and serum ferritin.
Conclusion.
The level of various nutritional biomarkers (vitamins A, C, E, and B12 and trace elements zinc, copper, selenium) was reduced in chronically transfused Egyptian thalassemic patient.
These patients should have periodic nutritional evaluation and supplementation.
Multicenter studies are highly recommended.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sherief, Laila M.& Abd El-Salam, Sanaa M.& Kamal, Naglaa M.& El safy, Osama& Almalky, Mohamed A. A.& Azab, Seham F.…[et al.]. 2014. Nutritional Biomarkers in Children and Adolescents with Beta-Thalassemia-Major : An Egyptian Center Experience. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-458399
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sherief, Laila M.…[et al.]. Nutritional Biomarkers in Children and Adolescents with Beta-Thalassemia-Major : An Egyptian Center Experience. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-458399
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sherief, Laila M.& Abd El-Salam, Sanaa M.& Kamal, Naglaa M.& El safy, Osama& Almalky, Mohamed A. A.& Azab, Seham F.…[et al.]. Nutritional Biomarkers in Children and Adolescents with Beta-Thalassemia-Major : An Egyptian Center Experience. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-458399
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-458399
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر