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The Emerging Role of Biotechnological Drugs in the Treatment of Gout
المؤلفون المشاركون
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-04-16
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
One of the most important therapeutic advances obtained in the field of rheumatology is the availability of the so-called bio(techno)logical drugs, which have deeply changed treatment perspectives in diseases such as rheumatoid arthritis and ankylosing spondylitis.
According to the steadily increasing attention on gout, due to well-established prognostic and epidemiology implications, in the last 5 years, the same change of perspective has been observed also for this disease.
In fact, several bio(techno)logical agents have been investigated both for the management of the articular gout symptoms, targeting mainly interleukin-1β, as well as urate-lowering therapies such as recombinant uricases.
Among the IL-1β inhibitors, the majority of studies involve drugs such as anakinra, canakinumab, and rilonacept, but other compounds are under development.
Moreover, other potential targets have been suggested, as, for example, the TNF alpha and IL-6, even if data obtained are less robust than those of IL-1β inhibitors.
Regarding urate-lowering therapies, the recombinant uricases pegloticase and rasburicase clearly showed their effectiveness in gout patients.
Also in this case, new compounds are under development.
The aim of this review is to focus on the various aspects of different bio(techno)logical drugs in gouty patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cavagna, Lorenzo& Taylor, W. J.. 2014. The Emerging Role of Biotechnological Drugs in the Treatment of Gout. BioMed Research International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-458681
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cavagna, Lorenzo& Taylor, W. J.. The Emerging Role of Biotechnological Drugs in the Treatment of Gout. BioMed Research International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-458681
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cavagna, Lorenzo& Taylor, W. J.. The Emerging Role of Biotechnological Drugs in the Treatment of Gout. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-458681
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-458681
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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