NSAID-Induced Enteropathy in Rheumatoid Arthritis Patients with Chronic Occult Gastrointestinal Bleeding : A Prospective Capsule Endoscopy Study
المؤلفون المشاركون
Bradna, Petr
Kopacova, Marcela
Baštecká, Drahomíra
Rejchrt, Stanislav
Bures, Jan
Tachecí, Ilja
Douda, Tomáš
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-07
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background.
The purpose of study was to evaluate the diagnostic yield of capsule endoscopy for NSAID-induced enteropathy and clinical, laboratory, and endoscopic characteristics of disease in patients with rheumatoid arthritis.
Methods.
37 rheumatoid arthritis patients (30 women; mean age 55) treated with NSAIDs (>1 month), presented with anaemia and/or positive faecal occult blood testing, entered the study and underwent capsule endoscopy (EndoCapsule; Olympus), laboratory tests, and filled in questionnaires.
Results.
The prevalence of NSAID-induced enteropathy diagnosed by capsule endoscopy was 68% (25/37), classified as mild (red spots or erosions) in 18 (49%), moderate (10–20 erosions) in 4 (11%), and severe enteropathy (>20 erosions or ulcers) in 3 (8%) patients.
We did not find statistically significant relationship between the enteropathy and gender, age, haemoglobin, leukocytes, albumin and CRP, or dyspepsia.
The difference between subgroups of NSAIDs according to the COX specificity was not statistically significant.
Conclusions.
Capsule endoscopy is a highly accurate noninvasive method for evaluation of NSAID-induced enteropathy.
It was revealed in a substantial section of the patients with rheumatoid arthritis and occult gastrointestinal bleeding, mostly classified as mild damage.
No simple clinical or laboratory markers of the presence or severity of NSAID-induced enteropathy were recognised.
This trial is registered with DRKS00004940.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tachecí, Ilja& Bradna, Petr& Douda, Tomáš& Baštecká, Drahomíra& Kopacova, Marcela& Rejchrt, Stanislav…[et al.]. 2013. NSAID-Induced Enteropathy in Rheumatoid Arthritis Patients with Chronic Occult Gastrointestinal Bleeding : A Prospective Capsule Endoscopy Study. Gastroenterology Research and Practice،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-458911
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tachecí, Ilja…[et al.]. NSAID-Induced Enteropathy in Rheumatoid Arthritis Patients with Chronic Occult Gastrointestinal Bleeding : A Prospective Capsule Endoscopy Study. Gastroenterology Research and Practice No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-458911
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tachecí, Ilja& Bradna, Petr& Douda, Tomáš& Baštecká, Drahomíra& Kopacova, Marcela& Rejchrt, Stanislav…[et al.]. NSAID-Induced Enteropathy in Rheumatoid Arthritis Patients with Chronic Occult Gastrointestinal Bleeding : A Prospective Capsule Endoscopy Study. Gastroenterology Research and Practice. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-458911
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-458911
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر