Acetylation of Phenols, Anilines, and Thiols Using Silica Sulfuric Acid under Solvent-Free Conditions

الملخص EN

Silica sulfuric acid was employed as a heterogeneous catalyst for the acetylation of a variety of phenols, amines, and thiols under solvent-free conditions at room temperature.

Deactivated substrates also acetylated rapidly, and the method showed the preferential selectivity for acetylation of amino group in the presence of hydroxyl groupinwhich no C-acylation was observed.