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Inhibitory Effect of the Hexane Fraction of the Ethanolic Extract of the Fruits of Pterodon pubescens Benth in Acute and Chronic Inflammation
المؤلفون المشاركون
Cardoso, Mara Lane Carvalho
da Rocha, Bruno Ambrósio
Outuki, Priscila Miyuki
Froehlich, Diego Lacir
Hoscheid, Jaqueline
Bersani-Amado, Ciomar Aparecida
da Silva, Maria Angélica Raffaini Cóvas Pereira
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-07-21
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Fruits of Pterodon pubescens Benth have been used traditionally for the treatment of rheumatism, sore throat, and respiratory disorders, and also as anti-inflammatory, analgesic, depurative, tonic, and hypoglycemic agent.
The study was aimed at evaluating the anti-inflammatory activity of the hexane fraction of an ethanolic extract of P.
pubescens fruits.
The oil from P.
pubescens fruits was extracted with ethanol and partitioned with hexane.
The anti-inflammatory activity was measured with increasing doses of the hexane fraction (FHPp) by using a carrageenan-induced rat model of pleurisy and a rat model of complete Freund's adjuvant-induced arthritis by using an FHPp dose of 250 mg/kg for 21 days.
Treatment with an FHPp resulted in anti-inflammatory activity in both models.
The results of biochemical, hematological, and histological analyses indicated a significant decrease in glucose, cholesterol, and triglycerides levels (18.32%, 34.20%, and 41.70%, resp.) and reduction in the numbers of total leukocytes and mononuclear cells.
The FHPp dose of 1000 mg/kg induced no changes in behavioral parameters, and no animal died.
The results of this study extend the findings of previous reports that have shown that administration of extracts and fractions obtained from species of the genus Pterodon exhibits anti-inflammatory activity and lacks toxicity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hoscheid, Jaqueline& Bersani-Amado, Ciomar Aparecida& da Rocha, Bruno Ambrósio& Outuki, Priscila Miyuki& da Silva, Maria Angélica Raffaini Cóvas Pereira& Froehlich, Diego Lacir…[et al.]. 2013. Inhibitory Effect of the Hexane Fraction of the Ethanolic Extract of the Fruits of Pterodon pubescens Benth in Acute and Chronic Inflammation. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-459317
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hoscheid, Jaqueline…[et al.]. Inhibitory Effect of the Hexane Fraction of the Ethanolic Extract of the Fruits of Pterodon pubescens Benth in Acute and Chronic Inflammation. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-459317
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hoscheid, Jaqueline& Bersani-Amado, Ciomar Aparecida& da Rocha, Bruno Ambrósio& Outuki, Priscila Miyuki& da Silva, Maria Angélica Raffaini Cóvas Pereira& Froehlich, Diego Lacir…[et al.]. Inhibitory Effect of the Hexane Fraction of the Ethanolic Extract of the Fruits of Pterodon pubescens Benth in Acute and Chronic Inflammation. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-459317
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-459317
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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