Successful Administration of Recombinant Human Soluble Thrombomodulin α (Recomodulin) for Disseminated Intravascular Coagulation during Induction Chemotherapy in an Elderly Patient with Acute Monoblastic Leukemia Involving the t(9;11)(p22;q23) MLLAF9 Translocation
المؤلفون المشاركون
Takagi, Kazutaka
Iwasaki, Hiromichi
Yamauchi, Takahiro
Tasaki, Toshiki
Ueda, Takanori
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-08-02
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Patients with acute myelogenous leukemia complicate with disseminated intravascular coagulation (DIC), not only at the time of the initially leukemia diagnosis, but also during induction chemotherapy.
In Japan, recently, a recombinant human soluble thrombomodulin alpha (Recomodulin) has been introduced as a new type of anti-DIC agent for clinical use in patients with hematological cancer or infectious disease.
We describe a 67-year-old female case in which 25,600 units of Recomodulin for 6 days were successfully administered for both initially complicating and therapy-induced DIC without any troubles of bleeding in an acute monoblastic leukemia (AML-M5a) patient with the MLL gene translocation.
Furthermore, the levels of DIC biomarkers recovered rapidly after the Recomodulin treatment.
Our case suggests that DIC control using Recomodulin is one of the crucial support-therapies during remission induction chemotherapy in patients with acute leukemia of which type tends to complicate extramedullary or extranodal infiltration having potential to onset DIC.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Takagi, Kazutaka& Tasaki, Toshiki& Yamauchi, Takahiro& Iwasaki, Hiromichi& Ueda, Takanori. 2011. Successful Administration of Recombinant Human Soluble Thrombomodulin α (Recomodulin) for Disseminated Intravascular Coagulation during Induction Chemotherapy in an Elderly Patient with Acute Monoblastic Leukemia Involving the t(9;11)(p22;q23) MLLAF9 Translocation. Case Reports in Hematology،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-459346
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Takagi, Kazutaka…[et al.]. Successful Administration of Recombinant Human Soluble Thrombomodulin α (Recomodulin) for Disseminated Intravascular Coagulation during Induction Chemotherapy in an Elderly Patient with Acute Monoblastic Leukemia Involving the t(9;11)(p22;q23) MLLAF9 Translocation. Case Reports in Hematology No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-459346
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Takagi, Kazutaka& Tasaki, Toshiki& Yamauchi, Takahiro& Iwasaki, Hiromichi& Ueda, Takanori. Successful Administration of Recombinant Human Soluble Thrombomodulin α (Recomodulin) for Disseminated Intravascular Coagulation during Induction Chemotherapy in an Elderly Patient with Acute Monoblastic Leukemia Involving the t(9;11)(p22;q23) MLLAF9 Translocation. Case Reports in Hematology. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-459346
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-459346
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر