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The Role of IL-6, 8, and 10, sTNFr, CRP, and Pancreatic Elastase in the Prediction of Systemic Complications in Patients with Acute Pancreatitis
المؤلفون المشاركون
Fisic, E.
Bilic-Zulle, L.
Licul, V.
Milic, S.
Stimac, Davor
Poropat, G.
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-02-12
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background and Aim.
Early assessment of severity in acute pancreatitis (AP) is a key measure to provide rational and effective management.
The aim of our study is to determine the prognostic value of interleukins (IL) 6, 8, and 10, soluble receptor for tumor necrosis factor (sTNFr), pancreatic elastase (E1), and C-reactive protein (CRP) as predictors of systemic complications in AP.
Patients and Methods.
A hundred and fifty patients with confirmed AP were enrolled in the study.
The severity of AP was defined according to Atlanta criteria.
Measurements of interleukins and sTNFr were performed on the first day of admission.
CRP and E1 levels were assessed on admission and after 48 hours.
ROC analysis was performed for all parameters.
Results.
Interleukins and sTNFr significantly differentiated patients with systemic complications from those without.
Elevation of IL-6 showed the highest significance as a predictor (P=0.001).
CRP and elastase levels did not differ between mild and severe cases on admission, but reached statistical significance when measured on the third day (P=0.002 and P=0.001, resp.).
Conclusion.
Our study confirmed that IL-6, IL-8, IL-10, and sTNFr measured on admission, and CRP and pancreatic elastase measured on third day of admission represent valuable prognostic factors of severity and systemic complications of AP.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fisic, E.& Poropat, G.& Bilic-Zulle, L.& Licul, V.& Milic, S.& Stimac, Davor. 2013. The Role of IL-6, 8, and 10, sTNFr, CRP, and Pancreatic Elastase in the Prediction of Systemic Complications in Patients with Acute Pancreatitis. Gastroenterology Research and Practice،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-460122
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fisic, E.…[et al.]. The Role of IL-6, 8, and 10, sTNFr, CRP, and Pancreatic Elastase in the Prediction of Systemic Complications in Patients with Acute Pancreatitis. Gastroenterology Research and Practice No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-460122
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fisic, E.& Poropat, G.& Bilic-Zulle, L.& Licul, V.& Milic, S.& Stimac, Davor. The Role of IL-6, 8, and 10, sTNFr, CRP, and Pancreatic Elastase in the Prediction of Systemic Complications in Patients with Acute Pancreatitis. Gastroenterology Research and Practice. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-460122
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-460122
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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