The Efficacy of Guanxinning Injection in Treating Angina Pectoris : Systematic Review and Meta-Analysis of Randomized Controlled Trials
المؤلفون المشاركون
Pan, Fongha
Lee, Simon Ming-Yuen
Leung, Siu-wai
Cui, Guozhen
Jia, Yongliang
Huang, Xiaohui
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-16، 16ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-03-24
دولة النشر
مصر
عدد الصفحات
16
التخصصات الرئيسية
الملخص EN
Objective.
The randomized controlled trials (RCTs) on Guanxinning injection (GXN) in treating angina pectoris were published only in Chinese and have not been systematically reviewed.
This study aims to provide a PRISMA-compliant and internationally accessible systematic review to evaluate the efficacy of GXN in treating angina pectoris.
Methods.
The RCTs were included according to prespecified eligibility criteria.
Meta-analysis was performed to evaluate the symptomatic (SYMPTOMS) and electrocardiographic (ECG) improvements after treatment.
Odds ratios (ORs) were used to measure effect sizes.
Subgroup analysis, sensitivity analysis, and metaregression were conducted to evaluate the robustness of the results.
Results.
Sixty-five RCTs published between 2002 and 2012 with 6064 participants were included.
Overall ORs comparing GXN with other drugs were 3.32 (95% CI: [2.72, 4.04]) in SYMPTOMS and 2.59 (95% CI: [2.14, 3.15]) in ECG.
Subgroup analysis, sensitivity analysis, and metaregression found no statistically significant dependence of overall ORs upon specific study characteristics.
Conclusion.
This meta-analysis of eligible RCTs provides evidence that GXN is effective in treating angina pectoris.
This evidence warrants further RCTs of higher quality, longer follow-up periods, larger sample sizes, and multicentres/multicountries for more extensive subgroup, sensitivity, and metaregression analyses.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jia, Yongliang& Leung, Siu-wai& Lee, Simon Ming-Yuen& Cui, Guozhen& Huang, Xiaohui& Pan, Fongha. 2013. The Efficacy of Guanxinning Injection in Treating Angina Pectoris : Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-16.
https://search.emarefa.net/detail/BIM-460129
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jia, Yongliang…[et al.]. The Efficacy of Guanxinning Injection in Treating Angina Pectoris : Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-16.
https://search.emarefa.net/detail/BIM-460129
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jia, Yongliang& Leung, Siu-wai& Lee, Simon Ming-Yuen& Cui, Guozhen& Huang, Xiaohui& Pan, Fongha. The Efficacy of Guanxinning Injection in Treating Angina Pectoris : Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-16.
https://search.emarefa.net/detail/BIM-460129
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-460129
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر