Susceptibility of Gardnerella vaginalis Biofilms to Natural Antimicrobials Subtilosin, ε-Poly-L-Lysine, and Lauramide Arginine Ethyl Ester
المؤلفون المشاركون
Wirawan, Ruth E.
Cheryian, Thomson
Sinko, Patrick J.
Algburi, Ammar
Turovskiy, Yevgeniy
Takhistov, Paul
Chikindas, Michael L.
المصدر
Infectious Diseases in Obstetrics and Gynecology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-09-17
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Bacterial vaginosis is a common vaginal infection associated with numerous gynecological and obstetric complications.
This condition is characterized by the presence of thick adherent vaginal biofilms, composed mainly of Gardnerella vaginalis.
This organism is thought to be the primary aetiological cause of the infection paving the way for various opportunists to colonize the niche.
Previously, we reported that the natural antimicrobials subtilosin, ε-poly-L-lysine, and lauramide arginine ethyl ester selectively inhibit the growth of this pathogen.
In this study, we used plate counts to evaluate the efficacy of these antimicrobials against established biofilms of G.
vaginalis.
Additionally, we validated and compared two rapid methods (ATP viability and resazurin assays) for the assessment of cell viability in the antimicrobial-treated G.
vaginalis biofilms.
Out of the tested antimicrobials, lauramide arginine ethyl ester had the strongest bactericidal effect, followed by subtilosin, with clindamycin and polylysine showing the weakest effect.
In comparison to plate counts, ATP viability and resazurin assays considerably underestimated the bactericidal effect of some antimicrobials.
Our results indicate that these assays should be validated for every new application.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Turovskiy, Yevgeniy& Cheryian, Thomson& Algburi, Ammar& Wirawan, Ruth E.& Takhistov, Paul& Sinko, Patrick J.…[et al.]. 2012. Susceptibility of Gardnerella vaginalis Biofilms to Natural Antimicrobials Subtilosin, ε-Poly-L-Lysine, and Lauramide Arginine Ethyl Ester. Infectious Diseases in Obstetrics and Gynecology،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-460308
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Turovskiy, Yevgeniy…[et al.]. Susceptibility of Gardnerella vaginalis Biofilms to Natural Antimicrobials Subtilosin, ε-Poly-L-Lysine, and Lauramide Arginine Ethyl Ester. Infectious Diseases in Obstetrics and Gynecology No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-460308
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Turovskiy, Yevgeniy& Cheryian, Thomson& Algburi, Ammar& Wirawan, Ruth E.& Takhistov, Paul& Sinko, Patrick J.…[et al.]. Susceptibility of Gardnerella vaginalis Biofilms to Natural Antimicrobials Subtilosin, ε-Poly-L-Lysine, and Lauramide Arginine Ethyl Ester. Infectious Diseases in Obstetrics and Gynecology. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-460308
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-460308
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر